# DataBase Shared Resource

> **NIH NIH P30** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2021 · $182,658

## Abstract

DATABASE SHARED RESOURCE: PROJECT SUMMARY
The function of the DataBase Shared Resource (DBSR) is to develop, integrate, and maintain a centralized,
cost-effective, and well-characterized research database encompassing all the Herbert Irving Comprehensive
Cancer Center (HICCC) tumor registries. Directed by Jeanine Genkinger, PhD and Katherine Crew, MD, MS,
the DBSR has, over the past five years, developed a standardized protocol with universal consent of individuals
with cancer or at risk for cancer to promote novel and innovative cancer research within the HICCC, as well as
the larger Columbia University Irving Medical Center (CUIMC) community. The DBSR provides oversight and
infrastructure for the development and maintenance of a cancer-related research database across multiple
cancer subspecialties including: (1) integration of all prior adult solid tumor registries into one standardized
protocol; (2) development of a retrospective cohort of patients through linkage of data from electronic health
records (EHRs) across multiple platforms and data warehouses (i.e., New York-Presbyterian Hospital [NYPH]
Tumor Registry) with existing residual tissue samples; and (3) development and maintenance of a prospective
cohort implemented through consenting, collecting biospecimens (e.g., blood, saliva) and epidemiologic data
(e.g., lifestyle factors), and linking to data from the EHR/NYPH Tumor Registry and residual tissue samples.
DBSR also coordinates research database-related services with other Shared Resources. In addition, DBSR
provides support to the research community by: (1) incorporating recruitment to ancillary studies in the cancer
clinics via recruitment staff, (2) reviewing requests to access the cancer-related research database via a
dedicated Scientific Review Committee and tracking utilization of requests (i.e., manuscripts published, funding
awarded), and (3) disseminating information about the cancer-related research database to the research and
lay community to promote novel and innovative cancer research. Over the current project period (2014-2019),
DBSR integrated 24 clinical registries into one overarching research database. Due to highly qualified and
bilingual recruiters, DBSR has met its accrual targets and enrolled over 4,700 individuals, from whom DBSR has
collected over 2,400 biospecimens, and over 2,600 questionnaires. To foster highly innovative research, the
DBSR has approved and fulfilled over 120 data and biospecimen requests and supported over 10 ancillary
studies through efficient enrollment and data extraction. Through this, the DBSR has supported several federally
funded grants. Over the current project period, the capabilities of the DBSR have been utilized by 35 HICCC
members and supported key data and insights for 31 HICCC member peer-reviewed publications, including five
papers with impact factor >10 and manuscripts in reference cancer journals (e.g., Cancer Epidemiology,
Biomarkers & Prevention, Clinical Cancer Res...

## Key facts

- **NIH application ID:** 10245179
- **Project number:** 5P30CA013696-46
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** Katherine D Crew
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $182,658
- **Award type:** 5
- **Project period:** 1997-07-04 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10245179

## Citation

> US National Institutes of Health, RePORTER application 10245179, DataBase Shared Resource (5P30CA013696-46). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10245179. Licensed CC0.

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