# Core 1: Biostatistics Core

> **NIH NIH P50** · JOHNS HOPKINS UNIVERSITY · 2021 · $89,541

## Abstract

PROJECT SUMMARY 
The goal of the GastroIntestinal Biostatistics and Bioinformatics Core (GI-BBC) is to 
provide wide-ranging, high-quality statistical and bioinformatics support to the GI 
SPORE. The primary aim of the GI-BBC is to assist GI SPORE investigators in the 
design, conduct and analysis of laboratory and clinical studies proposed in this SPORE 
application. The GI-BBC will focus its efforts on assisting both the clinical and laboratory 
investigators in translating their pre-clinic studies into clinical studies by providing state- 
of-the-art experimental designs and analyses through statistical consultation and in 
collaboration with respect to methodology, feasibility, analysis, and reporting of clinical 
and laboratory studies. In addition, the GI-BBC will serve as an ongoing resource for all 
GI-SPORE investigators. The Core will be led by Dr. Sugar and Dr. Scharpf and Dr. 
Rachel Karchin will act as a co-investigator. These GI-BBC faculty members have 
complementary areas of expertise: Dr. Sugar in biostatistics specializing in translation 
and clinical study design and analysis, Dr. Scharpf in the analysis of high-throughput 
genomic assays, Dr. Karchin in computational genetics. Ms. Amanda Blackford, a 
biostatistician in the Cancer Center, will assist Drs. Sugar and Scharpf in statistical 
analyses. David McKean, a Master's level bioinformatics specialist will assist Dr. 
Scharpf. Centralization of statistical needs within the GI-BBC core will provide SPORE 
investigators with open access to a team of statisticians with the skill set necessary to 
meet the current and future goals of the SPORE in a cost-effective manner. In addition, 
it will facilitate communication across SPORE projects, aiding the translation of research 
findings into the clinical setting.

## Key facts

- **NIH application ID:** 10246364
- **Project number:** 5P50CA062924-27
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** Robert B. Scharpf
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $89,541
- **Award type:** 5
- **Project period:** 1997-02-28 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10246364

## Citation

> US National Institutes of Health, RePORTER application 10246364, Core 1: Biostatistics Core (5P50CA062924-27). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10246364. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*