# Core Grant in Vision Research

> **NIH NIH P30** · VANDERBILT UNIVERSITY MEDICAL CENTER · 2021 · $772,594

## Abstract

PROJECT SUMMARY
 The Vanderbilt Vision Research Center (VVRC) was founded in 1989 as a cross-institutional,
interdisciplinary collaboration between Vanderbilt University and Vanderbilt University Medical Center. The
VVRC has a history innovative vision research, spanning the eye and its diseases to cognitive processing and
integration of visual information. Faculty from the School of Medicine, College of Arts & Science, School of
Engineering and the Peabody College of Education and Human Development combine through strong
institutional support and strategic faculty appointments to sustain excellence in vision science. We request
continued support for eight well-coordinated service modules in addition to our administrative module. Animal
Services, Histology, Instrumentation and Computation represent cores intrinsic to VVRC facilities, while
Genomics, Cell Imaging, In Vivo Imaging, and Proteomics utilize an internal scholarship system to subsidize
use of the world-class institutional cores for which Vanderbilt is known.
 The Animal Services Module (1) provides specialized surgical and daily services essential for our
investigators who use awake, behaving nonhuman primates or other large mammals. The Histology Module (2)
provides preparation, embedding, sectioning and staining of all tissues derived from visual structures in the eye
and brain. The Instrumentation Module (3) provides unique, customized apparatus and tools and provides
expertise in constructing digital interfaces for laboratory equipment. The Computation Module (4) provides
server maintenance, custom programming and coding for data analysis and machine interfacing, system
administration, and webpage-based applications. The Genomics Module (5) subsidizes use of VANTAGE, or
Vanderbilt Technologies for Advanced Genomics, and VANGARD, or Vanderbilt Technologies for Advanced
Genomics Analysis and Research Design, for high-throughput DNA and RNA services, biostatistical and
bioinformatic support, and data analysis and storage. The Cell Imaging Module (6) utilizes the Vanderbilt Cell
Imaging Shared Resource (CISR) and includes specialized confocal and laser-scanning microscopy along with
high-performance image processing. The In Vivo Imaging Module (7) utilizes the Vanderbilt University Institute
of Imaging Science (VUIIS), which offers several noninvasive resources through the Human Imaging Core and
the Center for Small Animal Imaging (CSAI). Finally, the Proteomics Module (8) supports use of the Mass
Spectrometry Research Center (MSRC), which comprises Proteomics, Mass Spec Tissue Imaging, and Mass
Spectrometry and provides high-throughput analysis of protein modifications, differential protein expression,
protein-protein interactions and localization, and biomarkers of disease. The Administrative Module ensures
continued smooth and stable operation of the VVRC research and training missions.
 Modules are directed by investigators with history of NEI funding, have talented and experienced ...

## Key facts

- **NIH application ID:** 10246437
- **Project number:** 5P30EY008126-34
- **Recipient organization:** VANDERBILT UNIVERSITY MEDICAL CENTER
- **Principal Investigator:** David J. Calkins
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $772,594
- **Award type:** 5
- **Project period:** 1997-04-01 → 2024-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10246437

## Citation

> US National Institutes of Health, RePORTER application 10246437, Core Grant in Vision Research (5P30EY008126-34). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10246437. Licensed CC0.

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