# Omic and Multidimensional Spatial Atlas of Metastatic Breast and Prostate Cancers

> **NIH NIH U2C** · OREGON HEALTH & SCIENCE UNIVERSITY · 2021 · $301,997

## Abstract

ABSTRACT - Administrative Core 
The Administrative Core will serve as the organization, integration, and evaluation hub of the OMS Atlas. This 
Core provides leadership, and supports and coordinates: (a) communications and integration within the OMS 
Atlas and with the Human Tumor Atlas Network (HTAN); (b) proposal management, reporting, and compliance 
activities; (c) oversight of budgetary and intellectual property issues; (d) unit milestone evaluation and 
integration, and coordination with the SMMART Clinical Trial; (e) trans-HTAN projects; (f) organization of the 
biomedical use case working group; (g) oversight of the OMS Atlas computational infrastructure and the Data 
and Resource Sharing Plan; (h) data access and publication plans, including dispute resolution; and (i) HTAN 
and External Advisory Committee (EAC) review. The Administrative Core will be led by Dr. Joe Gray (Contact 
Program Director/PI, and Characterization Unit Lead); Dr. Gordon Mills (PD/PI, SMMART Clinical Trial 
Director, and co-Lead Biospecimen Unit); Dr. Chris Corless (PD/PI and Lead Biospecimen Unit); Dr. Jeremy 
Goecks (PD/PI and Lead of the Data Analysis Unit); and Center Administrator, Dr. Heidi Feiler. Drs. Annette 
Kolodzie and Brett Johnson will manage integration of the SMMART clinical trial component, and biospecimen 
and data sharing, respectively, across the units. This Core will coordinate OMS Atlas participation in the HTAN 
programmatic meetings, such as HTAN Steering Committee meetings, annual Investigators meetings and site 
visits. For planning and evaluation, it will organize OMS Atlas meetings, including monthly unit progress 
meetings and Executive Committee meetings, and quarterly Steering Committee meetings, comprised of all 
key personnel. Meetings will be video conferenced to facilitate participation and discussion. In addition, the 
Administrative Core will oversee the Data and Resource Sharing Plan and development of the data networking 
infrastructure platform in the Analysis Unit that will integrate with the HTAN-Data Coordinating Center (HTAN- 
DCC) and the HTAN-Tissue Coordinating Center. The Administrative Core will coordinate publications of 
analyses of the OMS data that reveal specific resistance mechanisms. It will oversee trans-HTAN project 
development in collaboration with the OMS Atlas EAC and the HTAN. The Administrative Core will organize 
annual EAC meetings to provide guidance on OMS Atlas activities. This review will be coordinated with an 
annual retreat and HTAN site visit so the external advisors and HTAN leadership will have the opportunity to 
interact with researchers from all OMS Atlas sites. To facilitate collaboration, PIs from other HTAN centers, the 
HTAN-DCC and leaders of major cancer analysis generating programs (e.g., Cancer Systems Biology 
Consortium (CSBC), LINCS, PS-ON, TCGA, ICGC, BD2K, and CTD2) will also be invited. In summary, the 
Administrative Core will support and integrate activities between the ...

## Key facts

- **NIH application ID:** 10246894
- **Project number:** 5U2CCA233280-04
- **Recipient organization:** OREGON HEALTH & SCIENCE UNIVERSITY
- **Principal Investigator:** JOE W. GRAY
- **Activity code:** U2C (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $301,997
- **Award type:** 5
- **Project period:** 2018-09-19 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10246894

## Citation

> US National Institutes of Health, RePORTER application 10246894, Omic and Multidimensional Spatial Atlas of Metastatic Breast and Prostate Cancers (5U2CCA233280-04). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10246894. Licensed CC0.

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