# University of California Health Participation in the National COVID Cohort Collaborative (N3C)

> **NIH NIH UL1** · UNIVERSITY OF CALIFORNIA-IRVINE · 2020 · $498,289

## Abstract

PROJECT SUMMARY
Through this supplement, we will orchestrate a collective effort across the five CTSA Hubs at the University of
California (UC) Health to contribute data to, and become a strategic partner of, the National COVID Cohort
Collaborative (N3C). By combining the data resources and research informatics expertise at UC Davis, San
Francisco, Los Angeles, Irvine, and San Diego, UC Health is uniquely positioned to provide high-quality clinical
data of diverse patient populations across the State of California to help N3C fulfill its mission to “build a
centralized national data resource that the research community can use to study COVID-19 and identify
potential treatments as the pandemic continues to evolve.” The proposed work will leverage an existing UC-
wide initiative on curating the UC COVID Research Data Set (UC CORDS), a continuously updated HIPAA
Limited Data Set that contains comprehensive clinical information of all patients tested for COVID-19 at any
UC Health facility. To ensure high-quality and timely data delivery, we will create a UC-wide governance
structure to establish a master Data Transfer and Use Agreement (DTUA) with NCATS on behalf of all five UC
CTSA Hubs, in addition to coordinating research ethics reviews. We will also create an informatics task force
involving key stakeholders at each UC CTSA Hub to coordinate site-level data work. Data aggregation, quality
assurance, and submission will be performed by the UC Health Data Warehouse (UCHDW) team at the Center
for Data-Driven Insights and Innovation (CDI2) in the UC Office of the President.
Glossary
ACT Accrual to Clinical Trials
CDI2 Data-Driven Insights and Innovation
CDW Clinical Data Warehouse
CMBI Center for Biomedical Informatics
COVID-19 Coronavirus Disease 2019 (COVID-19)
CTSA Clinical and Translational Science Awards
DTUA Data Transfer and Use Agreement
EHR Electronic health records
i2b2 Informatics for Integrating Biology and the Bedside
N3C National COVID Cohort Collaborative
OMOP Observational Medical Outcomes Partnership
PCORnet National Patient-Centered Clinical Research
Network
SHRINE Shared Health Research Information Network
UC BRAID University of California Biomedical Research
Acceleration, Integration, and Development
UC CORDS University of California COVID Research
Data Set
UC Davis CTSC University of California, Davis Clinical
and Translational Science Center
UC Irvine ICTS University of California, Irvine Institute for
Clinical and Translational Science
UC ReX University of California Research Exchange
UCHDW University of California Health Data Warehouse
UCLA CTSI University of California, Los Angeles Clinical
and Translational Science Institute
UCSD ACTRI University of California, San Diego Altman
Clinical and Translational Research Institute
UCSF CTSI University of California, San Francisco
Clinical and Translational Science Institute

## Key facts

- **NIH application ID:** 10247238
- **Project number:** 3UL1TR001414-06S2
- **Recipient organization:** UNIVERSITY OF CALIFORNIA-IRVINE
- **Principal Investigator:** DAN M COOPER
- **Activity code:** UL1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $498,289
- **Award type:** 3
- **Project period:** 2015-08-15 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10247238

## Citation

> US National Institutes of Health, RePORTER application 10247238, University of California Health Participation in the National COVID Cohort Collaborative (N3C) (3UL1TR001414-06S2). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10247238. Licensed CC0.

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