# Indiana University Melvin and Bren Simon Cancer Center Support Grant

> **NIH NIH P30** · INDIANA UNIVERSITY INDIANAPOLIS · 2021 · $2,746,580

## Abstract

ABSTRACT, Overview and Essential Characteristics
The IU Simon Cancer Center is an NCI-designated Cancer Center that is dedicated to cancer research,
education, and patient care for the citizens of Indiana and beyond. Since our last review, the IUSCC has
substantially increased the depth and breadth of our science and cancer relevant research as evidenced by over
a 38% increase in NCI funding (Direct Costs), a 176% increase in our multi-PI grants while attracting over 30
new investigators in cancer research to our institution. We are the home to the country's first pathway-driven
SPORE that focuses on pediatric tumors and the birthplace to three active cancer consortia, including one that
links researchers from North America and sub-Saharan Africa. The IUSCC is composed of two basic programs,
Hematopoiesis and Hematologic Malignancies (HHM) and Tumor Microenvironment and Metastasis (TMM), and
two translational programs, Experimental and Developmental Therapeutics (EDT) and Cancer Prevention and
Control (CPC). We define our catchment area as the entire state of Indiana as patients come from each of the
92 counties and 89% of the counties have at least one patient entered on clinical trials.
Our community outreach and engagement activities have focused on the urban and rural populations of Indiana
with the diseases with the highest mortality in the state, (i.e. lung, breast and gastrointestinal cancers) as well
as behavioral risk factors, which adversely impact screening and prevention (e.g. tobacco and HPV
vaccinations). We focus on developing novel approaches for screening, treatment and symptom science using
"precision medicine" and expanding work in bioinformatics and medical informatics to address the increasing
complexity of understanding the genomic and clinical data. We embrace the vision of increasing the research
workforce in Indiana and globally through education from "Teens-to-Tenure" and the integration of clinical and
translational research in our strategic plan. This strategic plan, which has its underpinnings with education and
impact to our catchment area, is composed of four pillars that are foundational to the IUSCC. These pillars
include: 1) Biology to Bedside Research; 2); Precision Medicine; 3) Prevention, Early Detection and Population
Health: Local-Global Approaches; and 4) Health Care Disparities, Survivorship, and Symptom Science.

## Key facts

- **NIH application ID:** 10247597
- **Project number:** 5P30CA082709-22
- **Recipient organization:** INDIANA UNIVERSITY INDIANAPOLIS
- **Principal Investigator:** KELVIN P. LEE
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $2,746,580
- **Award type:** 5
- **Project period:** 1999-09-22 → 2024-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10247597

## Citation

> US National Institutes of Health, RePORTER application 10247597, Indiana University Melvin and Bren Simon Cancer Center Support Grant (5P30CA082709-22). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10247597. Licensed CC0.

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