# Proteomics

> **NIH NIH P30** · INDIANA UNIVERSITY INDIANAPOLIS · 2021 · $63,882

## Abstract

ABSTRACT, Proteomics Core (PC)
The Indiana University School of Medicine (IUSM) Proteomics Core (PC) is a mass spectrometry (MS)-centric
protein analysis center with extensive expertise in affinity-purification mass spectrometry methods and
quantitative proteomics. IUSM has recently purchased two state-of-the-art mass spectrometers, two ultra high-
pressure liquid chromatography systems, and a variety of ionization sources to facilitate innovative application
of proteomics methods to basic and clinical research questions for all researchers at IUSM, particularly IU Simon
Cancer Center (IUSCC) members. Our central goal is to apply and develop state-of-the-art proteomics methods
to measure system-wide changes in protein biology, as it relates to cancer biological questions. The proteomics
core and IUSCC leadership have developed the following specific aims to meet the critical needs of IUSCC
members for proteomics services: Specific Aim 1: To provide IUSCC users with state-of-the art proteomics
services with a focus on global proteome and phosphoproteome profiling; Specific Aim 2: To develop leading
edge proteomics services in chemoproteomics to facilitate drug discovery and drug characterization in IUSCC;
Specific Aim 3: To expand affinity-purification MS analysis for identification of high-confidence interacting
proteins; and Specific Aim 4: To develop, provide, and/or organize educational opportunities related to
proteomics technologies, experimental design and data analysis.

## Key facts

- **NIH application ID:** 10247609
- **Project number:** 5P30CA082709-22
- **Recipient organization:** INDIANA UNIVERSITY INDIANAPOLIS
- **Principal Investigator:** AMBER L. MOSLEY
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $63,882
- **Award type:** 5
- **Project period:** 1999-09-22 → 2024-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10247609

## Citation

> US National Institutes of Health, RePORTER application 10247609, Proteomics (5P30CA082709-22). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10247609. Licensed CC0.

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