# Community Outreach Core

> **NIH NIH U54** · HUNTER COLLEGE · 2021 · $103,227

## Abstract

PROJECT SUMMARY
Community Outreach Core
TUFCCC: Yin Tan, MD, MPH (Co-Leader) HC: Ming-Chin Yeh, PhD (Co-Leader)
 Community-Based Org: Marilyn A. Fraser, MD (Co-Leader)
Statistics in cancer health disparities are staggering in underserved minority populations. African American
(AA) face the highest incidence and death rates of various cancer compared with Non-Hispanic Whites (NHW);
African Americans have the highest incidence of colorectal cancer (CRC) with a 20% higher incidence and a
13% higher mortality rate compared with NHW. Moreover, the prevalence of liver cancer-related HCV is twice
as high in African Americans as in NHW population (3.0% vs 1.5%, respectively). Asian Pacific Americans
(APAs) have the highest incidence rates of liver cancer among all U.S. racial/ethnic groups, largely due to
chronic Hepatitis B (CHB) infection as a major identified risk factor. Prevalence rates of chronic hepatitis B
range from 8% to 16% in APAs vs 1% in NHW. APAs are 8-13 times more likely to develop liver cancer with
60% higher death rate than NHW. Although the national trend of colorectal cancer is declining, prevalence of
colorectal cancer among APAs has steadily increased. Hispanic Americans (HAs) also experience
substantial cancer disparities. From 2003 to 2011, Hispanic Americans had the highest increase in liver cancer
incidence (+35.8%), which has doubled compared to NHWs (19.3 vs. 9.3 in men, 7.2 vs. 3.2 in women per
100,000 population). In addition, CRC is the second most commonly diagnosed cancer among Hispanic
Americans. Unique social and structural determinants, such as lack of health insurance coverage, less
familiarity with U.S. health system, low socioeconomic status, or cultural and access barriers, often contribute
to the observed disparities among our targeted disparity populations. The proposed TUFCCC/HC Cancer
Outreach Core (COC) is an integral part of the TUFCCC/HC Regional Comprehensive Cancer Health Disparity
Partnership. The overall goal of Community Outreach Core is twofold: 1) strengthen community engagement
in outreach research and cancer control through effective community cancer education initiatives and outreach
activities to reduce cancer disparities among underserved African Americans, Asian Pacific Americans and
Hispanic populations in PA, NJ, NYC region, and 2) provide a robust and sustainable community-based
participatory research infrastructure for the TUFCCC/HC Partnership. Building on successful collaboration
between TUFCCC and HC during the Planning Phase and extensive collective experiences in working with
underserved communities, the COC will achieve the proposed goals through three major outreach strategies,
including strengthening community engagement in outreach research and cancer control, supporting and
integrating community CBPR research infrastructure with research projects/cores of the U54 Partnership, and
enhancing community outreach effort impact at individual, organization and community levels.

## Key facts

- **NIH application ID:** 10248422
- **Project number:** 5U54CA221704-04
- **Recipient organization:** HUNTER COLLEGE
- **Principal Investigator:** Ming-Chin Yeh
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $103,227
- **Award type:** 5
- **Project period:** 2018-09-18 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10248422

## Citation

> US National Institutes of Health, RePORTER application 10248422, Community Outreach Core (5U54CA221704-04). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10248422. Licensed CC0.

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