# Collaborative Pediatric Critical Care Research Network - Clinical Site

> **NIH NIH PL1** · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · 2021 · $81,775

## Abstract

PROJECT ABSTRACT - University of California Consortium
The University of California, San Francisco (UCSF) Benioff Children's Hospital has been a Clinical Site in the
Eunice Kennedy Shriver National Institutes of Child Health and Development (NICHD) Collaborative Pediatric
Critical Care Research Network (CPCCRN) since 2014 (3rd cycle) and is enthusiastic about participating as a
Clinical Hub in the newly organized and expanded network. During the 3rd cycle, Dr Anil Sapru (original PI)
relocated to University of California, Los Angeles (UCLA) and UCLA joined UCSF as a consortium site. More
recently UCSF has affiliated with the former Children's Hospital Oakland resulting in the new Benioff Children's
Hospitals at San Francisco (BCHSF) and Oakland (BCHO). Thus, BCHSF and BCHO, along with UCLA, will
comprise a clinical consortium or hub site in the present site application. We will work closely with our ancillary
site, University of California, Davis Children's Hospital. In combination with this partner, our site will provide
access to 104 PICU beds with approximately 4500 annual admissions, enabling us to participate fully in the
“Personalized Immunomodulation in Sepsis-induced MODS” trial described in the Overall Component of this
application. Our site proposal has three specific aims: Specific Aim 1. Actively collaborate in implementation
of CPCCRN, including participation on the Steering Committee and other committees, attendance at meetings,
facilitating contracting with the Data Coordinating Center, and complying with the standard operating
procedures and performance expectations of the network. Specific Aim 2. Provide opportunities for young
investigators to participate in CPCCRN meetings, committees, or trial implementation, with the goal of
developing these talented individuals into fundable clinician scientists. Specific Aim 3. Implement the
Personalized Immunomodulation in Sepsis-induced MODS trial, including enrollment of patients by trained
research staff, adhering to the study protocol, prompt data entry, and full compliance with Good Clinical
Practice (GCP) and other regulatory requirements.

## Key facts

- **NIH application ID:** 10248820
- **Project number:** 1PL1HD105462-01
- **Recipient organization:** UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH
- **Principal Investigator:** Patrick Sean McQuillen
- **Activity code:** PL1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $81,775
- **Award type:** 1
- **Project period:** 2021-08-13 → 2026-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10248820

## Citation

> US National Institutes of Health, RePORTER application 10248820, Collaborative Pediatric Critical Care Research Network - Clinical Site (1PL1HD105462-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10248820. Licensed CC0.

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