# Community-based Participatory Design of an HPV rapid diagnostic test for cervical cancer screening in South Florida

> **NIH NIH K01** · PURDUE UNIVERSITY · 2021 · $168,485

## Abstract

PROJECT SUMMARY:
Natalia Rodriguez, PhD, MPH, Research Assistant Professor at the University of Miami (UM), is a biomedical
engineer and global health researcher whose overarching career goal is to develop and improve upon
mechanisms for successful uptake and systemic adoption of innovative cancer detection technologies through
human-centered and community-based participatory design, in order to empower community health workforces,
strengthen health systems, and improve health outcomes at the population level. There is a pressing and unmet
need for an inexpensive HPV rapid diagnostic test (RDT) that is designed with the end-user in mind and
amenable to rapid systemic adoption in any given context. The research Dr. Rodriguez proposes entitled,
Community-based Participatory Design of a Human Papillomavirus (HPV) Rapid Diagnostic Test for Cervical
Cancer Screening in South Florida, combines community-based participatory research (CBPR) methodology
and human-centered design with health technology development to inform the design and translation of a rapid,
point-of-care HPV molecular diagnostic test for community use in cervical cancer screening.
 Dr. Rodriguez‘s previous work in technology development, specifically a molecular diagnostic platform
for point-of-care testing of HPV, in combination with her current work in health systems and community health
worker (CHW) training have prepared her to conduct the proposed research. Dr. Rodriguez proposes training
activities that include didactic and experiential learning on: 1) Qualitative research study design and CBPR
methodology; 2) Stakeholder engagement and human-centered design principles; 3) Implementation science
and translational research; 4) Designing and conducting randomized control trials. The proposed career
development plan will build upon her previous training to enhance her trajectory towards an independent
investigator in public health and translational sciences.
 An outstanding multidisciplinary mentorship team will guide Dr. Rodriguez through the proposed research
and training goals: Dr. Kobetz has expertise in CBPR, cancer disparities research and clinical trials, Dr. Daunert
in molecular diagnostic development, and Dr. Knaul in health systems and policy, stakeholder engagement, and
CHW training. The proposed research and career development plan utilize the breadth of resources at UM
including the Clinical and Translational Science Institute, the Sylvester Comprehensive Cancer Center, and the
laboratory and prototyping facilities and equipment of the Biomedical Nanotechnology Institute at UM (BioNIUM)
and UM’s Miller School of Medicine.
 The strong mentors, collaborators, and resources at UM ensure the success of the proposed research.
This award will provide Dr. Rodriguez with the training and preliminary data needed to be successful in a future
R01 study to validate the HPV RDT and will facilitate her development into an independent investigator and
leader in translational research...

## Key facts

- **NIH application ID:** 10249229
- **Project number:** 5K01CA241073-03
- **Recipient organization:** PURDUE UNIVERSITY
- **Principal Investigator:** Natalia Maria Rodriguez
- **Activity code:** K01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $168,485
- **Award type:** 5
- **Project period:** 2019-09-20 → 2024-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10249229

## Citation

> US National Institutes of Health, RePORTER application 10249229, Community-based Participatory Design of an HPV rapid diagnostic test for cervical cancer screening in South Florida (5K01CA241073-03). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10249229. Licensed CC0.

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