# A New Multi-functional and Connected Mobile App Guiding Acupressure Use for Self-management and Monitoring of Cancer Related Fatigue and Sleep Disturbances

> **NIH NIH R43** · 5 POINT APP · 2021 · $397,367

## Abstract

PROJECT SUMMARY
Fatigue and sleep disturbances, common, distressing, and debilitating symptoms of cancer and its treatment,
negatively impact physical, emotional, and social health of millions of cancer patients. Most of the 1.7 million
Americans diagnosed with cancer in 2020 will suffer cancer and treatment-related symptoms; up to 90%
receiving treatment experience fatigue; 30% may experience long-lasting fatigue. Sleep disturbances (affecting
up to 75% of patients) contribute to poor health and may exacerbate fatigue. Mounting evidence indicates that
acupressure, which is unfamiliar and infrequently used by cancer survivors, can reduce fatigue and improve
sleep. 5 Point App, Inc. is developing its first mobile health (mHealth) software, EnergyPoints, a patient
activation and educational app that offers an opportunity to mainstream acupressure—a beneficial strategy to
help cancer patients self-manage their symptoms. The EnergyPoints App will motivate and guide cancer
patients to implement daily acupressure protocols to self-manage fatigue and sleep disturbances. The app will
connect individual sleep and activity data synced from an Apple Watch/Fitbit with self-reports of symptoms,
allowing patients and clinical providers to monitor symptom response to acupressure self-treatment. The long-
term goal is to improve quality of life for cancer patients suffering from fatigue and sleep disturbances using
acupressure as a safe, universally affordable self-care technique. The team will first develop a fully functional
prototype app, validating data accuracy and debugging programming. Specific aim 1 is to confirm cancer
patients can accurately and consistently self-administer two acupressure protocols using the app. Specific aim
2 is to assess the usability of the app and the fitness tracker. Using an integrated agile, user-centered
approach, 20 patients with cancer who are experiencing fatigue will use the app to self-administer acupressure
(twice daily for 1 week) while wearing a fitness tracker. User performance video-recordings, and feedback via
talk-aloud session, debriefing, and exit interview, will be used to improve all prototype app features in sprints.
Results will provide evidence of feasibility and usability: specifically, the EnergyPoints prototype app can teach
and guide cancer patients to perform acupressure as directed, is acceptable, and can connect and accurately
share important health data from a fitness tracker. In a subsequent Phase 2 SBIR application, a clinical trial is
planned to examine efficacy of the app in improving fatigue and sleep in a sample of cancer patients.
Additionally, EnergyPoints App features will be extended by adding: 1) use of essential oils; 2) tailored
acupressure delivery; 3) clinical monitoring to integrate with cancer care; 4) social connection features, 5)
additional measures (e.g. pain, depression, activation) and 6) compatibility with other trackers (e.g. Amazon
Halo). Potential users include millions of...

## Key facts

- **NIH application ID:** 10255903
- **Project number:** 1R43CA261446-01
- **Recipient organization:** 5 POINT APP
- **Principal Investigator:** SUSAN L BECK
- **Activity code:** R43 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $397,367
- **Award type:** 1
- **Project period:** 2021-09-16 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10255903

## Citation

> US National Institutes of Health, RePORTER application 10255903, A New Multi-functional and Connected Mobile App Guiding Acupressure Use for Self-management and Monitoring of Cancer Related Fatigue and Sleep Disturbances (1R43CA261446-01). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/10255903. Licensed CC0.

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