ABSTRACT Small Animal Visual System Analysis Module Recent advances in genome editing technology are leading to an explosion of small animal models of human diseases. These animal models, when characterized efficiently and correctly, will benefit investigations that elucidate disease mechanisms and lead to exciting discoveries of therapeutic interventions. The Small Animal Visual System Analysis Module (SAVSAM) of the Baylor College of Medicine (BCM) Vision Core has been expanded to provide cutting edge instrumentation and expert services that are too big and specialized for individual labs to carry. The technologies and services covered in SAVSAM include spectral domain optical coherence tomography (SDOCT), in vivo and ex vivo electroretinography (ERG), equipment that tests optokinetic reflex (OKR), patch clamp recording, water-maze behavior testing, biochromatography, quantitative immunoblotting, and mass spectrometry. The SAVSAM promotes cross-disciplinary collaborations among BCM vision researchers by allowing both in vivo and non-invasive services to help gauge structural and functional integrity of visual systems in their small animal models. The SAVSAM is also committed to training users and enhancing visual system testing capabilities at BCM.