# Community Outreach and Education Core (Core B)

> **NIH NIH P50** · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · 2022 · $116,114

## Abstract

The Community Outreach and Education Core of the Center for Male Reproductive Epigenomics will be located
and operated though Los Angeles Biomedical Research Institute (LA Biomed) at Harbor-UCLA Medical Center
located in South West Los Angeles. This Core will develop outreach and education programs designed to
disseminate information on the effects of life styles on the epigenetic regulation of sperm gene expression that
may be transmitted to the next generation. Our theme is to promote “Healthy life style, Healthy sperm
epigenome, Healthy babies”. Building on our prior collaboration and community-academic partnership, we plan
to achieve our goals by engaging youths, high school and college students, and younger adults from our
communities to disseminate information on reproductive epigenomics and their effects on the next generation.
We have four aims: Aim 1. Promote and sustain bidirectional knowledge sharing between the community and
academic institutions by providing opportunities for networking and developing a community specific
dissemination plan for evidence based information on how obesity and inactivity change the sperm epigenome
transmitting unhealthy phenotype and epigenotype to the next generation. Aim 2. Create educational programs,
workshops and conferences to engage younger adults, college and high school students (future parents) to
disseminate information on “healthy life styles, healthy reproductive epigenome; healthy babies”. With our
partners we will conduct community-partnered research conferences and workshops for younger adults, and
summer program for high school and college students to provide knowledge transfer on the impact of
environment on epigenetics? how improvement in the environment may reverse maladaptive epigenetic
changes? and how epigenetics are linked to intergenerational transmission of disease phenotype? Aim 3.
Develop a community focused website for the Center for Male Reproductive Genomics. Working with our
community partners, academic partners at the University of Nevada Reno and the University of Texas San
Antonio, we will develop a culturally and racially sensitive website to provide information on the role of
epigenomics in reproductive health in general and impact of sperm epigenomics on next generation’s health.
Aim 4. Establish the governance and operation structure of the Community Core Advisory Council that
strengthens existing partnerships and builds new bridges between community and academia for education and
research.

## Key facts

- **NIH application ID:** 10260437
- **Project number:** 5P50HD098593-03
- **Recipient organization:** LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
- **Principal Investigator:** CHRISTINA C. WANG
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $116,114
- **Award type:** 5
- **Project period:** 2019-09-13 → 2025-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10260437

## Citation

> US National Institutes of Health, RePORTER application 10260437, Community Outreach and Education Core (Core B) (5P50HD098593-03). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10260437. Licensed CC0.

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