CORE A: ADMINISTRATIVE & PROGRAM ENRICHMENT – SUMMARY/ABSTRACT This Core 1) provides effective leadership, administration and management of the Center; 2) supports an External Advisory Panel of distinguished scientists who will provide review and recommendations to the executive leadership of the Center; 3) engages in outreach activities, including workshops, courses, lectures and symposia; 4) facilitates dissemination of Center resources and research findings to the Gerontological community; 5) collaborates with other funded Nathan Shock Centers; 6) supports an inter-Nathan Shock Center Geropathology Research Resource (GRR). The Center Co-PIs, Drs. Rabinovitch and Kaeberlein jointly direct the Core activities. An Executive Committee assists in making policy decisions and is responsible for selection of Pilot Proposals. The External Advisory Panel of nationally and internationally respected gerontologists provides external review and advice.