# PROTOCOL REVIEW AND MONITORING SYSTEM (Core-010)

> **NIH NIH P30** · UT SOUTHWESTERN MEDICAL CENTER · 2020 · $80,143

## Abstract

Harold C. Simmons Cancer Center 
Protocol Review and Monitoring System (PRMS) 
Project Summary/Abstract 
The goal of the Protocol Review and Monitoring System (PRMS) is to ensure the highest scientific quality of 
clinical oncology research at UTSW and consists of three Cancer Center Protocol Review and Monitoring 
Committees (PRMCs), the Data and Safety Monitoring Committee (DSMC), and the administrative support 
services of the Clinical Research Office. These entities are overseen by the Clinical Cancer Research 
Committee, which reports to the Cancer Center's Deputy Director. The SCC has three PRMCs; two “general” 
committees, each of which meets monthly, and one reserved for Population Studies. PRMC1 and PRMC2 
have the same responsibilities, but were created with staggered meeting dates so as to allow more timely 
review and approval of new protocols. The Population Sciences PRMC is responsible for protocols related to 
Population Sciences and Cancer Control. 
The three PRMCs review and monitor all cancer-related clinical studies for scientific merit prior to IRB review. 
The PRMCs have the authority to open protocols that meet the scientific merit and scientific priorities of the 
SCC, and to close protocols that do not demonstrate scientific progress. The focus of the PRMCs is on 
scientific merit, study prioritization, and progress of Cancer Center clinical trials. Studies which have already 
undergone rigorous peer review at the national level, such as NCI-approved national cooperative group studies 
are reviewed administratively by the PRMC Chair.

## Key facts

- **NIH application ID:** 10260737
- **Project number:** 3P30CA142543-10S3
- **Recipient organization:** UT SOUTHWESTERN MEDICAL CENTER
- **Principal Investigator:** Carlos L Arteaga
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $80,143
- **Award type:** 3
- **Project period:** 2010-08-03 → 2021-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10260737

## Citation

> US National Institutes of Health, RePORTER application 10260737, PROTOCOL REVIEW AND MONITORING SYSTEM (Core-010) (3P30CA142543-10S3). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10260737. Licensed CC0.

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