# Tissue Management Shared Resource

> **NIH NIH P30** · UT SOUTHWESTERN MEDICAL CENTER · 2020 · $570,465

## Abstract

Harold C. Simmons Cancer Center 
Tissue Management Shared Resource (Translational Research Resource) 
Project Summary/Abstract 
The Tissue Management Shared Resource was established in 2004 to provide IRB-approved centralized 
tissue procurement services for specimens derived from consented human participants. Over 22,000 tissue 
specimens and bodily fluids, from over 50 different tissue types including breast, lung, prostate, kidney, 
bladder, colon, pancreas, blood, pleural fluid, urine and bone marrow have been collected since its 
establishment. In terms of demographics, specimens were obtained from Caucasian (72%), African-American 
(24%) and Hispanic participants (16%). Of the tissues collected, 56% of specimens are derived from female 
participants. Although the basic functions and goals of the Tissue Management Shared Resource remain 
essentially unchanged, the capabilities of the facility have been significantly expanded to support the growing 
needs of Simmons Cancer Center members and facilitate translational research activities. To facilitate this 
growth, Tissue Management Shared Resource has moved to a new location that provides additional space for 
equipment and staff. The equipment has been updated to accommodate increased and changing research 
needs. Additionally, tissue banking and annotation of specimens has been extensively expanded. Specimen 
related data are captured and stored in our tissue management database, caTissue Plus, and are correlated 
with clinical information through the Simmons Cancer Center's clinical research data warehouse (i2b2) as part 
of the UTSW Center for Translational Medicine (CTM), which is the institutional CTSA (Clinical & Translational 
Science Award). This tool links caTissue Plus data with EPIC Clarity (the electronic medical record), Oncolog 
(the university tumor registry database), CoPath (the anatomical pathology database), CancerGeneConnect 
(the familial genetics database) and other disease-specific databases. Due to this robust infrastructure, 
biospecimens are automatically annotated with demographic, pathological, and clinical data so that interested 
investigators can perform basic sample availability queries of this database in a de-identified manner through a 
secure web interface.

## Key facts

- **NIH application ID:** 10260741
- **Project number:** 3P30CA142543-10S3
- **Recipient organization:** UT SOUTHWESTERN MEDICAL CENTER
- **Principal Investigator:** Adam Yopp
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $570,465
- **Award type:** 3
- **Project period:** 2010-08-03 → 2021-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10260741

## Citation

> US National Institutes of Health, RePORTER application 10260741, Tissue Management Shared Resource (3P30CA142543-10S3). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10260741. Licensed CC0.

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