# Data Coordinating Center for Type 1 Diabetes TrialNet

> **NIH NIH U01** · UNIVERSITY OF SOUTH FLORIDA · 2020 · $2,792,647

## Abstract

Project Summary/Abstract
This application requests support for the continuing operations of the TrialNet
Coordinating Center (TNCC) at the University of South Florida. The University of South
Florida has served as the Coordinating Center for TrialNet since October, 2008. The
primary objective of TrialNet is to prevent or delay initial onset and/or progression of type
1 diabetes (T1D) by preserving insulin-producing beta cells in individuals at elevated risk
and those who have been newly diagnosed with T1DM. To achieve this goal, TrialNet
designs and implements prevention and interventional clinical trials intended to test
treatments that may preserve remaining insulin secretion in recently diagnosed
individuals (new-onsets). The TNCC provides epidemiological, biostatistical, operational
and administrative expertise and advice to the clinical centers, reference laboratories
and the NIDDK which include the following tasks: 1) study-wide communications,
procurement and dissemination of study materials, and related activities 2) data
management and records maintenance; 3) clinical site and central laboratories
monitoring; 4) data analyses; 5) preparation of study reports and papers for publication;
6) implementation of procedures to evaluate management, methodology, and cost-
effectiveness of procedures utilized by the TNCC; and 7) periodic meetings. This
application provides support for enhancements and upgrades for communication, data
collection, editing, processing, analysis, and reporting for TrialNet studies and
operations including data quality, protocol adherence and data confidentiality, and
provide for implementation and procedures for coordinating submission of samples
and data from the participating Clinical and Affiliate Centers to the TrialNet Central
Laboratories and NIDDK Repository.

## Key facts

- **NIH application ID:** 10261304
- **Project number:** 3U01DK106993-03S2
- **Recipient organization:** UNIVERSITY OF SOUTH FLORIDA
- **Principal Investigator:** JEFFREY P KRISCHER
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $2,792,647
- **Award type:** 3
- **Project period:** 2015-09-30 → 2024-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10261304

## Citation

> US National Institutes of Health, RePORTER application 10261304, Data Coordinating Center for Type 1 Diabetes TrialNet (3U01DK106993-03S2). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10261304. Licensed CC0.

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