# Administrative Core

> **NIH NIH P30** · WAKE FOREST UNIVERSITY HEALTH SCIENCES · 2021 · $386,843

## Abstract

Administrative Core – Project Summary
 The Wake Forest Alzheimer’s Disease Research Center (WF ADRC) provides a comprehensive, integrated
infrastructure to facilitate research aimed at identifying the causes of AD, and elucidating the role of
vascular/metabolic factors in transitions from normal aging to AD and other dementias. The WF ADRC also
provides resources to better understand disease heterogeneity and the multi-faceted impact of health
disparities on AD risk. The Administrative Core ensures that ADRC scientific and programmatic goals are
achieved by providing visionary oversight and effective governance to all Center activities, and scientific
direction to the Center as a whole. The Core will be directed by an Executive Committee, whose members
include the Director, Associate Directors, Core and Service Leaders, and the Program Manager. The
Executive Committee will be guided by an Internal Advisory Committee (IAC) composed of institutional
leaders who meet regularly to facilitate the achievement of ADRC aims and promote the growth of AD
research at WF. The Core will be also guided by an External Advisory Committee (EAC), chosen in
consultation with the NIA and consisting of members of other ADRCs and scientific leaders. The EAC will
meet annually to review WF ADRC program goals and progress. We will also seek input about ADRC
engagement with our community and participants through our Community and Participant Advisory Boards.
 Expansion of AD-related research and impactful utilization of valuable scientific resources are important
goals for all ADRCs. The Administrative Core Committee for Resource Utilization and Research EXpansion
(CRUX) oversees a coordinated series of activities to ensure that ADRC resources contribute to high-impact
research and that new translational scientists are brought into the field. In the past cycle, the CRUX facilitated
the rapid and successful integration of our new ADRC into the larger ADRC network, providing data and
biospecimen resources to the National Alzheimer’s Coordinating Center (NACC), the National Centralized
Repository for AD (NCRAD), other ADRCs and AD investigators world-wide. Through its distinctive theme and
innovative phenotyping, our ADRC contributes to National Alzheimer’s Project Act (NAPA) Research
Milestones involving metabolic/vascular factors, health disparities, translational models and trial design.
 WF ADRC’s ability to achieve its scientific and educational mission depends on the efficacy of its
Administrative Core. In its inaugural cycle, Core leaders developed and led vigorous interdisciplinary research
and educational programs. We have established effective Executive and Internal Advisory Committees,
launched a successful pilot program that has drawn creative new investigators to AD research, and established
multiple high-impact collaborations. Our comprehensive activities to date demonstrate that Administrative Core
members have the vision, influence, and commitment to ensure ...

## Key facts

- **NIH application ID:** 10262848
- **Project number:** 1P30AG072947-01
- **Recipient organization:** WAKE FOREST UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** SUZANNE CRAFT
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $386,843
- **Award type:** 1
- **Project period:** 2021-08-15 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10262848

## Citation

> US National Institutes of Health, RePORTER application 10262848, Administrative Core (1P30AG072947-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10262848. Licensed CC0.

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