# Data Management and Statistical Core

> **NIH NIH P30** · UNIVERSITY OF PENNSYLVANIA · 2021 · $229,645

## Abstract

Data Management and Statistical Core
Summary/Abstract
The Data Management and Statistical (DMS) Core described here is an integral part of the University of
Pennsylvania School of Medicine (Penn) Alzheimer’s Disease (AD) Research Center (ADRC). The goal of the
DMS Core in this application is to support the data management, statistical, bioinformatics, database, and
related computational needs of Penn ADRC investigators and ADRC Developmental Project awardees. The
services provided by the DMS Core include: (a) support for data form/questionnaire design and development,
database development and management, big data (e.g., genomic and imaging data) integration, data entry,
database audit trail, database security, database backup, and stringent data quality control procedures, (b)
computing and programming support for all Penn ADRC activities, including implementation and integration of
hardware and software upgrades necessary for data management and research, routine and archival off-site
backup of computing systems central to the Penn ADRC, (c) biostatistical support for all study aspects from
inception to publication, including development of study design, performing sample size and power
calculations, and performing analyses of the ADRC data, (d) provide statistical training to ADRC trainees, (e)
promoting an effective working relationship between the Penn ADRC, other NIA funded AD Research Centers
and the National Alzheimer’s Coordinating Center (NACC). Thus, the DMS Core plays an important and
significant role in the Penn ADRC that is critical to research on AD and related disorders, subjects with mild
cognitive impairment (MCI) and cognitively normal (CN) controls conducted by Penn ADRC investigators and
their collaborators at other ADRCs as well as to the continuation of an effective working relationship with
NACC.

## Key facts

- **NIH application ID:** 10264229
- **Project number:** 1P30AG072979-01
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** Sharon Xiangwen Xie
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $229,645
- **Award type:** 1
- **Project period:** 2021-08-15 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10264229

## Citation

> US National Institutes of Health, RePORTER application 10264229, Data Management and Statistical Core (1P30AG072979-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10264229. Licensed CC0.

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