# Outreach, Recruitment and Engagement Core

> **NIH NIH P30** · UNIVERSITY OF PENNSYLVANIA · 2021 · $115,937

## Abstract

Outreach, Recruitment and Engagement Core Summary
Alzheimer’s disease (AD) is undergoing a scientific and cultural revolution. Discoveries about the disease’s
pathophysiology are transforming our understanding of AD as well as how clinicians diagnose and treat it, and
the US has a sustained commitment to a national Alzheimer’s plan. Milestones are in place to achieve
ambitious goals that include transformations to the delivery of care and, by 2025, the discovery of methods to
effectively treat and prevent the disease. Gene and biomarker-based clinical trials have been launched for
persons with dementia, and also those in the MCI stage and even the “preclinical” stage. At the same time,
research shows there is substantial heterogeneity within and overlap between AD and other late-life
neurodegenerative diseases, giving credence to the concept of AD and related dementias (AD/ADRD). And
yet, despite all this progress, all this knowledge, persons with dementia and their families still struggle to find
decent care, must cope with sometimes crushing stigma, and experience social and economic disparities. A
major focus of the Penn ADRC is to promote and disseminate research that advances this revolutionary
understanding of AD/ADRD, explains the heterogeneity of the disease, improves care, and addresses stigma
and disparities. This focus informs the overarching goals of the Penn ADRC’s Outreach, Recruitment and
Engagement (ORE) Core: to advance research, to promote public understanding, and to foster better ways for
patients, families, and America to live with AD/ADRD. We will achieve this goal in part through collaboration
with the Administrative Core and REC to support the development of Penn ADRC staff and
professionals’ knowledge, attitudes, and skills related to communications, cognitive aging, AD/ADRD, the
stages of these diseases, care and caregiving, stigma, and diversity, equity, and inclusion. Working with
the Clinical and Administrative Cores and community partners, we will develop and implement
effective outreach and engagement programs to educate the public, people living with MCI and dementia, and
caregivers and families about AD/ADRD, as well as to build support structures and promote research that
address the distinct challenges AD/ADRD poses to well-being and autonomy. The Black or African-American
community will be an emphasis of this work. We will also work with Penn ADRC investigators and their
collaborators to develop strategies and tactics to recruit and retain subjects for AD/ADRD research protocols,
including clinical trials. This work, in collaboration with our community partners and the Clinical, Data
Management and Statistical, Neuropathology, Genomics, Neuroimaging, and Biomarker Cores, has an
emphasis on research to collect data measuring the social determinants of brain health in addition to genetic
material and biomarkers of AD/ADRD.

## Key facts

- **NIH application ID:** 10264231
- **Project number:** 1P30AG072979-01
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** JASON H KARLAWISH
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $115,937
- **Award type:** 1
- **Project period:** 2021-08-15 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10264231

## Citation

> US National Institutes of Health, RePORTER application 10264231, Outreach, Recruitment and Engagement Core (1P30AG072979-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10264231. Licensed CC0.

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