# Experimental Models Core

> **NIH NIH P30** · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · 2021 · $81,837

## Abstract

EXPERIMENTAL MODELS MODULE
Summary
The purpose of the Experimental Models (EM) Module is to provide expert service and
assistance for a large variety of in vivo testing and procedures, help facilitate all experiments
using animal models performed by MVRC investigators, and to enable them to develop new
interdisciplinary projects. Specific Aims are: 1) To provide expert services and assistance,
through the use of specialized equipment and experienced personnel, for a large variety of
surgical and non-surgical procedures for experimental vision research in mice, rats, rabbits,
cats, dogs, pigs and non-human primates, 2) To provide training to all investigators on
established procedures and assist investigators to develop new procedures, including new
surgical methods, drug delivery and generation of mito-mice, 3) To serve as a resource center
for fostering new collaborations among MVRC scientists and clinicians, and for sharing animal
models, biological tissues and genotyping protocols, 4) To consult and assist with IACUC
protocols, including protocol writing and compliance. Experienced personnel and specialized
equipment are available in this module for vision researchers. This module is essential for
numerous basic science and translational research studies at BPEI, as indicated by its
extensive use by most of our NEI-funded investigators. In the last funding period, the EM
module was used to generate data that was reported in numerous publications and included in
new grant awards. Furthermore, this module has been essential in developing novel
electrophysiological and behavioral assessment of vision in rodents, for creating inducible
animal models of glaucoma, diabetes, and macular degeneration, testing novel gene therapies,
and investigating environmental influences on animal models of retinal disease through the use
of the rodent smoking machine and specific nutrition modifications. This module will continue to
provide an essential resource for cutting-edge research of MVRC investigators.

## Key facts

- **NIH application ID:** 10264379
- **Project number:** 2P30EY014801-17A1
- **Recipient organization:** UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
- **Principal Investigator:** Abigail S Hackam
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $81,837
- **Award type:** 2
- **Project period:** 2004-05-01 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10264379

## Citation

> US National Institutes of Health, RePORTER application 10264379, Experimental Models Core (2P30EY014801-17A1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10264379. Licensed CC0.

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