PROJECT SUMMARY/ABSTRACT The Cancer Registry Shared Resource Core (CRSRC) will serve a key role in identifying and characterizing cancer disparities in the multiethnic populations of Guam and Hawai‘i. The overall objective of the CRSR is to provide key infrastructure support for cancer research and outreach activities of the Pacific Island Partnership for Cancer Health Equity (PIPCHE). The CRSRC meets the requirements of PIPCHE shared resources to enhance the ability to conduct cancer disparities research. The CRSRC represents a partnership between the Guam Cancer Registry (GCR) and the Hawai‘i Tumor Registry (HTR), the central cancer registries of the Territory of Guam and the State of Hawai‘i, respectively. This partnership has been critical to the development of the GCR as a fully functioning registry through technical support and training provided by the HTR and through the establishment of statutory authority for cancer reporting and securing territorial funding. The CRSRC subsequently played a critical role in the development of the Pacific Regional Central Cancer Registry covering the US Affiliated Pacific Islands. The CRSRC serves as a critical resource for PIPCHE research and outreach. The CRSRC generates high- quality cancer surveillance data through which cancer disparities can be identified and characterized. This information is key to establishing PIPCHE research and outreach priorities. The CRSR also provides key support for research and outreach activities. The CRSRC will continue to serve as an important Core of the PIPCHE. Specific Aim 1. Provide cancer data and related support for PIPCHE research projects (full and pilot) and outreach activities. Specific Aim 2. Build capacity for cancer surveillance and health disparities research at the University of Guam (UOG) and the University of Hawai‘i Cancer Center (UHCC). This alignment will allow for a synergy and sharing of data that would not be possible otherwise.