# Infectious Disease Assay Development Core

> **NIH NIH P20** · UNIVERSITY OF KANSAS LAWRENCE · 2021 · $183,333

## Abstract

PROJECT SUMMARY
The Infectious Disease Assay Development (IDAD) laboratory for studying the Chemical Biology of Infectious
Disease provides expertise on assay development and screening of small molecule libraries. The compounds
identified from the screen serve as chemical tools or probes for dissecting mechanism of action and
modulating infectious disease targets. In addition to the availability of physical and technical resources to
perform chemical screening, it is critical to design, develop and optimize assays that truly reflect specific
target function in infectious disease biology. The University of Kansas has an established and successful HTS
facility with excellent intellectual and physical resources. The Infectious Disease Assay Development core
established in Phase I of CBID funding takes advantage of these assets and expands the current capabilities
by providing additional expertise and dedicated research space to develop assays against novel disease
relevant targets. The overall goal of this core is to provide a full array of expertise, facilities, services, and
training in the area of HTS assay design, development, validation, small and large-scale screening for
organism (cell) based or biochemical infectious disease targets. The expected outcomes of these efforts are
miniaturized and validated assays suitable for automated large-scale screening that can be performed
internally or externally. The expertise and resources are also expected to enable investigators to develop
competitive proposals in response to funding opportunity announcements for discovery of chemical probes or
therapeutic agents from Department of Defense, or NIH. Additionally, hits generated through successful
assay development and small molecule screening efforts serve as starting points for the Computational
Chemical Biology and the Synthetic Chemical Biology cores for successful development of optimized
compounds for use as chemical probes and pre-therapeutics for infectious diseases.

## Key facts

- **NIH application ID:** 10270501
- **Project number:** 2P20GM113117-06
- **Recipient organization:** UNIVERSITY OF KANSAS LAWRENCE
- **Principal Investigator:** Anuradha Roy
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $183,333
- **Award type:** 2
- **Project period:** 2016-05-15 → 2026-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10270501

## Citation

> US National Institutes of Health, RePORTER application 10270501, Infectious Disease Assay Development Core (2P20GM113117-06). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10270501. Licensed CC0.

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