PROJECT SUMMARY This second phase of the COBRE CBID is designed to 1) provide a world-class environment to provide researchers access to key techniques relevant to the chemical biology of infectious disease; 2) support and enable junior faculty to build successful research programs; 3) enhance infectious disease research throughout the regional scientific community by providing core facility access to all interested researchers. The mission of the Computational Chemical Biology (CCB) Core is to provide computational resources and expertise to enhance the productivity of researchers studying infectious diseases.