# DATA COORDINATING CENTER FOR THE STUDY OF PREGNANCY AND NEONATAL HEALTH (SPAN)

> **NIH NIH N01** · TECHNICAL RESOURCES INTERNATIONAL, INC. · 2020 · $255,763

## Abstract

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), 
Division of Intramural Population Health Research (DIPHR) requires data coordinating services for 
the Study of Pregnancy And Neonatal health (SPAN). SPAN is a prospective pregnancy cohort 
recruiting women in early pregnancy and retaining them throughout pregnancy with potential for 
long-term follow-up. The Study has three specific aims -
1) Paternal Contribution to DOHaD (DAD aim): Determine paternal cardiovascular risk and semen 
epigenetic factors associated with fetal growth, neonatal anthropometry, and placental 
characteristics;
2) Genetics of fetal Growth And Placental aging (gGAP aim): Identify genetic mechanisms underlying 
fetal growth, neonatal anthropometry, and placental epigenetic aging; and
3) Timing of delivery for GDM (Gestational Diabetes Mellitus) (TIME aim): Perform a clinical trial 
using  response adaptive randomization to determine the optimal timing of delivery for gestational 
diabetes complicated pregnancies between 37-39 weeks relative to neonatal morbidity and perinatal 
mortality.
This initiative is for the data coordinating services that will ultimately provide the final 
dataset and statistical analyses of the data that will be collected from the SPAN Study. This study 
involves multiple study sites that are responsible for recruitment and enrollment. The data 
coordinating center (DCC) (this task order) is responsible for organizing a data safety and 
monitoring board (DSMB) for the trial component. The web-based data collection system will be
established by the NICHD’s Clinical Trial Database (CTDB, https://ctdb.nichd.nih.gov/ctdb/).

## Key facts

- **NIH application ID:** 10271386
- **Project number:** 275201800013I-P00002-759401900125-1
- **Recipient organization:** TECHNICAL RESOURCES INTERNATIONAL, INC.
- **Principal Investigator:** DANIEL MOLINA
- **Activity code:** N01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $255,763
- **Award type:** —
- **Project period:** 2019-09-17 → 2024-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10271386

## Citation

> US National Institutes of Health, RePORTER application 10271386, DATA COORDINATING CENTER FOR THE STUDY OF PREGNANCY AND NEONATAL HEALTH (SPAN) (275201800013I-P00002-759401900125-1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10271386. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*