# START UP, PREPARATION, AND TEST ENROLLMENT FOR THE TIMING OF DELIVERY (TIME) AIM OF THE STUDY OF PREGNANCY AND NEONATAL HEALTH (SPAN)

> **NIH NIH N01** · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · 2020 · $946,992

## Abstract

The Division of Intramural Population Health Research (DIPHR) at the Eunice Kennedy Shriver 
National Institute of Child Health & Human Development (NICHD) designs and conducts original 
epidemiological, behavioral, and biostatistical research encompassing several research domains such 
as human reproduction and development, pregnancy and related complications, pediatric and 
adolescent health and behaviors, and methodologic research relevant for our mission. The Division 
comprises three intramural research branches, Epidemiology, Biostatistics & Bioinformatics, and 
Social and Behavioral Sciences, and its mission is to design and implement original research with 
the potential for high impact findings that impact public health.

Under the developmental origins of health and disease (DOHaD) hypothesis, early life exposures can 
“program” an individual for health and chronic disease risk through cellular adaptations to 
biological processes. Prenatal exposures and genetic factors impact fetal growth and development 
and neonatal health, important determinants of life-long health and disease. We propose an approach 
to examine a) the father’s role, b) placental determinants, and c) timing of delivery in relation 
to fetal and neonatal health and development. A cohort study will be performed to collect common 
data elements from approximately 10,728 pregnant women and their neonates and approximately 3825 
male partners with a randomized trial conducted in women with gestational diabetes (approximately 
3450 women, an addition of 2730). African American women will be oversampled (~4250). It is anticipated that multiple
study sites will be established.

## Key facts

- **NIH application ID:** 10271530
- **Project number:** 275201800009I-0-759402000001-1
- **Recipient organization:** UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH
- **Principal Investigator:** ROBERT SILVER
- **Activity code:** N01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $946,992
- **Award type:** —
- **Project period:** 2020-09-28 → 2021-09-27

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10271530

## Citation

> US National Institutes of Health, RePORTER application 10271530, START UP, PREPARATION, AND TEST ENROLLMENT FOR THE TIMING OF DELIVERY (TIME) AIM OF THE STUDY OF PREGNANCY AND NEONATAL HEALTH (SPAN) (275201800009I-0-759402000001-1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10271530. Licensed CC0.

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