# Core C:  Neuroimaging Resource Core

> **NIH NIH P50** · UNIVERSITY OF MICHIGAN AT ANN ARBOR · 2021 · $571,742

## Abstract

CORE C: ABSTRACT
The Neuroimaging Resource Core (NRC; Core C) will provide support for Projects I and III of the University
of Michigan Udall Center by performing the acquisition, processing, and parametric analysis and interpretation
of all human subjects in vivo positron emission tomography (PET) and magnetic resonance imaging (MRI) data.
The specific goals of the NRC are:
1) To perform [11C]DTBZ vesicular monoaminergic transporter type-2 dopamine transporter and [18F]FEOBV
 vesicular acetylcholine transporter PET on Parkinson disease (PD) subjects and age- and gender-matched
 (NC) subjects at baseline and at follow-up.
2) To perform MRI, including T1- and T2-weighted, diffusion weighted (DWI), and resting state functional
 connectivity (rs-fMRI) sequences on PD subjects and age- and gender-matched NC subjects at baseline and
 at follow-up.
3) To perform parametric quantification of physiological parameters from the PET data for subsequent statistical
 analysis in Projects I and III.
4) To perform parametric quantification of anatomical and functional parameters from the MRI data for
 subsequent statistical analysis in Projects I and III.
5) Coordinate neuroimaging data transfer and analysis from the University of Groningen (the Netherlands)
 Dutch Parkinson and Cognition (DUPARC) study.

## Key facts

- **NIH application ID:** 10282003
- **Project number:** 1P50NS123067-01
- **Recipient organization:** UNIVERSITY OF MICHIGAN AT ANN ARBOR
- **Principal Investigator:** Martijn L. T. M. Muller
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $571,742
- **Award type:** 1
- **Project period:** 2021-09-30 → 2026-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10282003

## Citation

> US National Institutes of Health, RePORTER application 10282003, Core C:  Neuroimaging Resource Core (1P50NS123067-01). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10282003. Licensed CC0.

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