# Purchase of a high-density electroencephalography (EEG) and neuromodulation system for use in an institutional core facility

> **NIH NIH S10** · BOSTON CHILDREN'S HOSPITAL · 2021 · $484,422

## Abstract

ABSTRACT
This grant application requests funding for the purchase of a high-density electroencephalography (EEG) system
to reside in the Human Neurophysiology Core at Boston Children's Hospital. The EEG system offers state-of-
the-art technology that will allow investigators flexibility in experimental design to incorporate event related
potentials, magnetic resonance imaging (MRI) co-acquisition, transcranial magnetic stimulation (TMS)
application and physiology co-registering into high density EEG collection. The equipment selected has been
optimized for EEG biomarker collection in pediatric populations, including infants, young children, children with
neurodevelopmental delays and neuropsychiatric symptomatology. Importantly, the equipment will be located
within a Core facility staffed with experts in the design, collection and analysis of EEG data enabling users to
obtain impactful results related to a broad array of NIMH funded research aims.
EEG is being incorporated into an increasing number of research studies due to the capacity of this technique
to yield high quality data reflecting neural function and connectivity from sensitive populations. Biomarkers of
disease state, prognostics, stratification and treatment response have been identified in a number of
neuropsychiatric disorders including autism spectrum disorder, ADHD, psychotic disorders and
depression/anxiety. Furthermore, considerable EEG research is being undertaken specifically for therapeutic
indications in combination with physiological measures (heart rate, galvanic skin response), TMS and MRI neuro-
feedback. The realization of these research goals, however, is dependent on the collection of standardized,
reproducible data, which is dependent on high quality equipment with built-in validation capabilities and deep
technical expertise. To this end, availability of the state-of-the art equipment outlined here within a core setting
makes incorporation of EEG based biomarkers and therapeutic applications possible for all investigators focused
on improving mental health outcomes.

## Key facts

- **NIH application ID:** 10283029
- **Project number:** 1S10MH124734-01A1
- **Recipient organization:** BOSTON CHILDREN'S HOSPITAL
- **Principal Investigator:** MUSTAFA SAHIN
- **Activity code:** S10 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $484,422
- **Award type:** 1
- **Project period:** 2021-08-01 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10283029

## Citation

> US National Institutes of Health, RePORTER application 10283029, Purchase of a high-density electroencephalography (EEG) and neuromodulation system for use in an institutional core facility (1S10MH124734-01A1). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/10283029. Licensed CC0.

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