# THE INFORMATICS, DATA ANALYSIS, AND STATISTICS CORE (IDASC)

> **NIH NIH U19** · WASHINGTON UNIVERSITY · 2021 · $1,040,293

## Abstract

ABSTRACT FOR IDASC
The Informatics, Data Analysis, and Statistics Core (IDASC) will implement the Human Connectome Project’s
data analysis approach for the Aging Adult Brain Connectome (AABC) Project’s multi-modal imaging data. It will
archive the imaging data as it is collected by the Integrated Data Acquisition Core (IDAC) and provide feedback
to the IDAC on any data quality concerns as a part of its initial quality control. The IDASC will also curate and
manage biological, sociological, and behavioral measures from the Genetics and Multi-omics Specimens Core
(GMSC) and IDAC. The HCP’s brain imaging preprocessing pipelines will be run on the imaging data when it
has been accepted by the database. This includes preprocessing for structural, functional, diffusion, and ASL
MRI data. The IDASC will then perform quality control on these preprocessing results. The IDASC will also
develop cross-sectional and longitudinal data analysis pipelines to generate multi-modal Imaging Data
Phenotypes (IDPs) representing brain architectural/morphometric, functional, and connectivity measures at the
levels of brain areas, functional networks, and white matter tracts. Using these imaging measures together with
the biological, sociological, and behavioral measures collected and generated by the IDAC and GMSC, the
IDASC will assist the 4 sub-projects with generation of optimized longitudinal statistical models to address their
specific hypotheses about interactions between brain, behavior/sociological, and biological factors that
contribute to Alzheimer’s Disease (AD) or other dementias. The IDASC will also share data at the conclusion of
the project.

## Key facts

- **NIH application ID:** 10283066
- **Project number:** 1U19AG073585-01
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** Daniel Scott Marcus
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $1,040,293
- **Award type:** 1
- **Project period:** 2021-09-30 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10283066

## Citation

> US National Institutes of Health, RePORTER application 10283066, THE INFORMATICS, DATA ANALYSIS, AND STATISTICS CORE (IDASC) (1U19AG073585-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10283066. Licensed CC0.

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