# Functional neurovascular coupling in a mouse model of Alzheimer's Disease

> **NIH NIH R01** · STATE UNIVERSITY NEW YORK STONY BROOK · 2021 · $315,637

## Abstract

Goal of Proposed Research
 Alzheimer’s disease (AD) is the most common neurodegenerative disease, presenting with
progressive and irreversible memory loss and dementia. Although medications and management
strategies can temporarily improve symptoms, no cure so far exists. Therefore, there is a high demand
for underlying the cause, pathological conditions and behavioral symptoms of AD for advancing possible
preventions and treatments. The central goal of the proposed research is to determine functional
neurovascular coupling of the dentate gyrus and its underlying neural circuit mechanism in a mouse
model of AD.

## Key facts

- **NIH application ID:** 10285083
- **Project number:** 3R01AG066912-02S1
- **Recipient organization:** STATE UNIVERSITY NEW YORK STONY BROOK
- **Principal Investigator:** Shaoyu Ge
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $315,637
- **Award type:** 3
- **Project period:** 2020-05-01 → 2025-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10285083

## Citation

> US National Institutes of Health, RePORTER application 10285083, Functional neurovascular coupling in a mouse model of Alzheimer's Disease (3R01AG066912-02S1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10285083. Licensed CC0.

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