# Training in the Science of Health Development

> **NIH NIH T32** · OHIO STATE UNIVERSITY · 2021 · $120,752

## Abstract

Summary
The Ohio State University College of Nursing T32 (7/1/20-6/30-25) provides research training on health
development. The specific aims of the training program are to: 1) prepare trainees to conduct rigorous
research with a particular emphasis on health development during sensitive and critical periods of health
development across the life span; 2) prepare trainees to develop and implement ethical research; 3) prepare
trainees to successfully translate the science of health development into clinical practice and health policy in
order to improve health outcomes; and 4) increase the number and strengthen the scientific foundation of early
career nurse scientists. Our aim for this administrative supplement is to: Add 1 predoctoral and 1 postdoctoral
trainee, each with a research focus on the examination of the effect of lifecourse exposures and health
determinants on Alzheimer’s disease (AD) and Alzheimer’s disease related dementias (ADRD), including AD
and ADRD risk and cognitive changes in later life. This additional aim will address the specific review criteria of
NOT-AG-20-034 in these ways: 1) The proposed additional trainees would work within the scope of the active
training grant, taking the same courses but with the specific mentorship assignment to training faculty with
expertise in aging, AD/ ADRD, exposures to adverse events across the lifecourse, health determinants, and
health outcomes (e.g. pain perception, social isolation, and impaired cognitive function); 2) The work will focus
on predictors, mechanisms, and mediators of AD/ADRD; and 3) The work of the trainees will build on faculty
expertise and on-going research, leading to future studies (F31 and K applications; R awards) to further
investigate relationships and develop interventions to mediate the effects of lifecourse adversities and health
determinants on the occurrence and/or severity of AD/ADRD. The pre- and postdoctoral trainees selected for
funding supported by this supplement will have a unique opportunity to work within a health development
framework to promote optimal outcomes for a significant health concern – Alzheimer’s disease and Alzheimer’s
disease-related dementia. Through a combination of didactic coursework, directed research residencies,
mentorship, skill-building workshops, research seminars, and independent research projects, trainees will
develop competencies to conduct state-of-the-art research in the science of health development focused on
AD/ADRD. Senior research mentors with active, federally-funded research programs in AD/ADRD related to
health determinants, mechanistic processes, and/or health outcomes, will guide trainees in their studies and
work closely with trainees to study how health determinants intersect to influence health development in
AD/ADRD, and to use this knowledge to examine ways to optimize health outcomes.

## Key facts

- **NIH application ID:** 10287576
- **Project number:** 3T32NR014225-06A1S1
- **Recipient organization:** OHIO STATE UNIVERSITY
- **Principal Investigator:** MARY E HAPP
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $120,752
- **Award type:** 3
- **Project period:** 2013-07-01 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10287576

## Citation

> US National Institutes of Health, RePORTER application 10287576, Training in the Science of Health Development (3T32NR014225-06A1S1). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10287576. Licensed CC0.

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