# Bicoastal Marmoset Breeding Center

> **NIH NIH U24** · JOHNS HOPKINS UNIVERSITY · 2021 · $298,186

## Abstract

Nonhuman primates (NHP) are crucial animal models for research on Alzheimer’s disease and its related
dementias because of their closest evolutionary relatives of humans, with whom they share anatomical,
physiological, and gene interactions features. The common marmoset (Callithrix jacchus) is a NHP model of
increasing importance for aging research. This new world primate provides some unique advantages for the
study of aging and aging-related disorders, including its relatively short lifespan among all the NHP used in
biomedical research. There has been an increasing number of investigators who are currently using or would
like to use marmosets as a model system to study aging and age-related diseases including Alzheimer’s
disease. However, there is a significant bottleneck for the research in this field. There are currently no reliable
distributors of marmosets for biomedical research in the country. The situation is even direr for researchers
who need access to aging marmosets. Recognizing such a bottleneck, NIH has recently funded two marmoset
breeding programs including the parent award of this application (“Bicoastal Marmoset Breeding Center”, U24-
MH123423). The goal of the proposed project is to fill the gap in the availability of aging marmosets for the
study of Alzheimer’s disease and its related dementias. We could use this center to develop a resource of
aging marmosets for Alzheimer's disease studies. This resource will be extremely valuable to the scientific
community studying Alzheimer's disease and its related dementias.

## Key facts

- **NIH application ID:** 10289057
- **Project number:** 3U24MH123423-02S1
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** XIAOQIN WANG
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $298,186
- **Award type:** 3
- **Project period:** 2021-06-01 → 2022-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10289057

## Citation

> US National Institutes of Health, RePORTER application 10289057, Bicoastal Marmoset Breeding Center (3U24MH123423-02S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10289057. Licensed CC0.

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