# Novel actions of neurosteroids on GABA (A) receptor trafficking

> **NIH NIH R01** · TUFTS UNIVERSITY BOSTON · 2021 · $53,830

## Abstract

Project Summary
This application is for a diversity supplement to the R01 NS108378, entitled “Novel actions of
neurosteroids on GABAAR trafficking” the PIs of which are Dr. Paul Davies and Dr. Stephen Moss
at Tufts University. The diversity candidate is Noell, a beginning pre-doctoral student in the lab of
Dr. Moss. Noell qualifies as a diversity candidate due to Guamanian classification and being a
first-generation college graduate having grown up in Guam, a U.S. rural area. This supplement is
to fund Noell’s first years in the lab for her to: 1) receive mentorship and training to advance in
pursuit of a career in science, 2) work on preliminary experiments to submit a NRSA F31
fellowship. Dr. Stephen Moss has trained 20 graduate students, many whom are independent
investigators, and has a well-respected track record of mentorship. Noell’s project is directly
related to aims of the parent grant, which centers on the role that neurosteriods play in mediating
the phospho-dependent regulation of GABAAR membrane trafficking. To do this, she will learn
and apply techniques in electrophysiology and biochemistry. Overall, this project will give Noell
broad exposure to contemporary methodologies used in “cutting edge” neuroscience research
and prepare her for a career as an independent investigator. Other mentorship interactions
between Noell and Dr. Moss funded by the supplement include building presentation skills, writing
grants and scientific publications, ability to design experiments, exposure to the field through
invited speakers, and interactions with pharmaceutical industry collaborators. The funding will
importantly provide Noell with enrichment opportunities so she can connect with others in the
broader neuroscience community. The diversity supplement will bridge Noell’s path towards a
positive future in science and continue to build diversity at Tuft’s University. The activities in
mentorship and enrichment made possible will be critical in Noell’s development as an
independent investigator.

## Key facts

- **NIH application ID:** 10290964
- **Project number:** 3R01NS108378-08S1
- **Recipient organization:** TUFTS UNIVERSITY BOSTON
- **Principal Investigator:** Paul Andrew Davies
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $53,830
- **Award type:** 3
- **Project period:** 2021-01-01 → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10290964

## Citation

> US National Institutes of Health, RePORTER application 10290964, Novel actions of neurosteroids on GABA (A) receptor trafficking (3R01NS108378-08S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10290964. Licensed CC0.

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