# Oklahoma Shared Clinical and Translational Resources

> **NIH NIH U54** · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · 2021 · $1,759,106

## Abstract

The pandemic caused by the novel coronavirus SARS-CoV-2 has resulted in substantial global morbidity and
mortality including in Oklahoma and caused unprecedented interruptions in nearly all aspects of our lives.
COVID-19 has demonstrated considerable disparities based on age and certain chronic illnesses as well as
other social determinants of health. The population of the state of Oklahoma is at particular risk to SARS-CoV-
2 due to its large rural population, strained healthcare system, and poor overall health. Rural populations in
general are medically underserved, older, and experience significant health disparities that overlap with those
comorbid conditions that can result in severe cases or even death from the infection. The Oklahoma Shared
Clinical and Translational Resources (OSCTR) and its long-standing community-engaged research programs
and partnerships are perfectly positioned to contribute to the knowledge base necessary to improve the
effectiveness of interventions to increase testing in underserved and vulnerable populations. We have
designed an approach that allows us not only to collect essential information about community, provider, and
patient-relevant impediments to SARS-CoV-2 diagnostic testing but also to meet the critical need to increase
testing in our state as rapidly as possible. The Community-engaged Approaches to Testing in Community and
Healthcare settings for Underserved Populations (CATCH-UP) program will involve both practice-based and
community-based approaches to maximize the reach of the RADx-UP consortium, broaden the potential
perspectives that could be captured, and compare the effectiveness of strategies. The interventions will be
pragmatic to allow CATCH-UP to respond to changing attitudes, barriers, and environments as the pandemic
progresses as well as expected technology developments to produce more effective viral testing that can
provide rapid results to patients. The practice-based intervention will utilize our existing research infrastructure
to assist 50 small primary care practices to implement guidelines-based testing and patient education about
COVID-19 and risk mitigation strategies. Our community-based approach is designed to rapidly respond to
community testing needs by deploying mobile testing sites that will provide operational support to increase the
efficiency and the existing capacity for state-wide testing by Oklahoma’s public health authorities. Together, we
estimate that the CATCH-UP program will result in at least 105,000 SARS-CoV-2 tests performed during the
first year of implementation. A comprehensive, ongoing evaluation will be performed to analyze patient and
provider attitudes, barriers and facilitators of viral testing, identified health disparities caused by COVID-19,
effectiveness of the intervention in both settings, and to allow robust collaboration with other RADx-UP
consortium sites.

## Key facts

- **NIH application ID:** 10293114
- **Project number:** 3U54GM104938-09S4
- **Recipient organization:** UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
- **Principal Investigator:** JUDITH A JAMES
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $1,759,106
- **Award type:** 3
- **Project period:** 2021-07-01 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10293114

## Citation

> US National Institutes of Health, RePORTER application 10293114, Oklahoma Shared Clinical and Translational Resources (3U54GM104938-09S4). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10293114. Licensed CC0.

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