# Gestational Diabetes Mellitus, Perinatal Depression, and Offspring Neurodevelopmental Phenotype

> **NIH NIH K99** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2021 · $130,842

## Abstract

PROJECT SUMMARY
This K99 application aims to determine pathways by which gestational diabetes mellitus (GDM) and prenatal
depression affect postpartum maternal mental health, neonatal brain function, and toddler brain-behavioral
development. There is a bidirectional association between GDM and depression which affect approximately
10% and 13% of women in the United States respectively and disproportionately affect women from ethnic and
racial minority groups. Both conditions are independently associated with adverse neurodevelopmental
outcomes in offspring including increased risk for social-emotional and attentional deficits. Despite the

## Key facts

- **NIH application ID:** 10301733
- **Project number:** 1K99HD103910-01A1
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** Lauren Christine Shuffrey
- **Activity code:** K99 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $130,842
- **Award type:** 1
- **Project period:** 2021-08-06 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10301733

## Citation

> US National Institutes of Health, RePORTER application 10301733, Gestational Diabetes Mellitus, Perinatal Depression, and Offspring Neurodevelopmental Phenotype (1K99HD103910-01A1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10301733. Licensed CC0.

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