# Husbandry and Transgenics Core

> **NIH NIH U01** · UNIVERSITY OF MASSACHUSETTS AMHERST · 2021 · $65,851

## Abstract

SUMMARY / ABSTRACT – Husbandry and Transgenics Core
The core will support the needs of the U19 by developing new methods for large scale culture of Berghia and
Aiptasia animals, and by supplying Berghia expressing fluorescent fusion sensors, from injected mRNA or from
DNA, through transgenesis. Although insertion, editing and stable expression of transgenes into animal genomes
has had a transformative impact on modern biology, a major factor limiting ongoing application of marine animals
in biomedical research is the lack of genetic tools for manipulating gene function. This core will develop several
innovations to supply researchers in the Berghia Brain Project with wildtype and transgenic animals. Thus, the
core will develop several tools necessary for the use of Berghia as a bona fide marine model system for
neuroscience.

## Key facts

- **NIH application ID:** 10302202
- **Project number:** 1U01NS123972-01
- **Recipient organization:** UNIVERSITY OF MASSACHUSETTS AMHERST
- **Principal Investigator:** Deirdre C Lyons
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $65,851
- **Award type:** 1
- **Project period:** 2021-09-15 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10302202

## Citation

> US National Institutes of Health, RePORTER application 10302202, Husbandry and Transgenics Core (1U01NS123972-01). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10302202. Licensed CC0.

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