# Core-009

> **NIH NIH P30** · UNIVERSITY OF SOUTHERN CALIFORNIA · 2021 · $175,458

## Abstract

The Translational Pathology Core has been continuously under the leadership of Dr. Sue Ellen Martin since its 
founding in 1998. This NCI-funded Shared Resource provides a single point of access for Cancer Center 
members needing tissue procurement and banking services. The specific aims of the Core are to: 1) procure, 
bank, process, track, and distribute both fresh/frozen and formalin-fixed, paraffin embedded (FFPE) normal 
and tumor tissue biospecimens necessary for laboratory-based, epidemiological, and hospital-based clinical 
studies being conducted by USC Norris Cancer Center members; 2) procure, maintain, and track discarded 
FFPE tumor tissue blocks from local regional hospitals identified through the Cancer Surveillance Program 
(CSP) for the population-based LA Residual Tissue Repository (RTR), which corresponds directly to the 
catchment area; 3) ensure that all studies utilizing tissue have appropriate documented IRB approval and that 
protected health information (PHI) is not released unless there is a signed written Informed Consent; and 4) 
incorporate innovations in tissue procurement and banking methodology to meet investigator-led research. The 
Core continues to have three components, or Arms: Adult, Pediatric and Population-Based. Together, these 
Arms provide an integrated, single stop service. 
Accomplishments during the project period include: 1) increased usage by Cancer Center members with peerreviewed 
grants. In the most recent reporting year (FY 2013-2014), 91 Cancer Center members used the Core, 
of which 53 (58%) had peer-reviewed funding. This is an increase of 140%, from the prior project period; 2) 
higher chargebacks. User fees account for 27% of the total budget, up from 17% over the project period; and 
3) increased collection and distribution of both fresh/frozen and FFPE tissues. This has contributed to 
significant research advances by Cancer Center members in understanding of the mechanisms involved in 
carcinogenesis, particularly in gastric, colorectal, urothelial and lung cancers, neuroblastoma and Hodgkin’s 
lymphoma.

## Key facts

- **NIH application ID:** 10303171
- **Project number:** 3P30CA014089-45S7
- **Recipient organization:** UNIVERSITY OF SOUTHERN CALIFORNIA
- **Principal Investigator:** CARYN LERMAN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $175,458
- **Award type:** 3
- **Project period:** 1996-12-01 → 2021-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10303171

## Citation

> US National Institutes of Health, RePORTER application 10303171, Core-009 (3P30CA014089-45S7). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10303171. Licensed CC0.

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