# Administrative Core

> **NIH NIH P01** · BOSTON UNIVERSITY MEDICAL CAMPUS · 2021 · $451,709

## Abstract

PROJECT SUMMARY/ABSTRACT
Alcohol use, common among PLWH, plays an increasingly important role in the risk for and management of
HIV-associated comorbidities. Unhealthy drinking can exacerbate two highly prevalent HIV-related
comorbidities/co-occurring conditions, chronic pain and physical inactivity, which in turn, can intensify alcohol
use and affect physical and mental function in PLWH. We propose the Boston Alcohol Research
Collaboration on HIV/AIDS – Comorbidity Center (Boston ARCH CC) as an extension of our Boston
Alcohol Research Collaboration on HIV/AIDS (ARCH) cohort launched in 2011 and renewed in 2016 with
funding from NIAAA. In Boston ARCH CC we target in randomized trials these two modifiable conditions, pain
and physical inactivity, that have a critical impact on a variety of other HIV-related comorbidities. We will also
support secondary analyses of the existing Boston ARCH cohort, and provide support and mentoring to
trainees and investigators accessing the cohort. The Administrative Core will be responsible for the day-to-day
management of the Boston ARCH CC and the operation of its components. In addition to the Administrative
Core, Boston ARCH CC elements include two Research Project Components (clinical trials), and a
Biostatistics and Data Management Core that leads our secondary analysis and training missions. The specific
aims of the Administrative Core are to: 1) Provide a rich research environment for Boston ARCH CC
investigators and trainees, and assure efficient progress of high-quality alcohol and HIV comorbidity/co-
occurring condition science; 2) Centralize support for Research Project Component clinical trial implementation
(e.g. Data Safety Monitoring, digital clinical trial recruitment and enrollment, ecological momentary
assessments, alcohol biomarker tests), beyond what would be achievable by individual stand-alone projects; 3)
Facilitate secondary data analysis, data sharing, and publication from analyses of Boston ARCH cohort data
related to pain, physical inactivity, and physical and mental health function; 4) Offer resources and mentoring
for early career investigators interested in engaging in alcohol and HIV research; 5) Engage in collaborative
science within and beyond the Boston ARCH CC. The Administrative Core, with its scientific and
administrative leadership and coordinated activities, will be essential for assuring that Boston ARCH CC
achieves its goals to reduce alcohol and HIV-associated comorbidities.

## Key facts

- **NIH application ID:** 10304667
- **Project number:** 1P01AA029546-01
- **Recipient organization:** BOSTON UNIVERSITY MEDICAL CAMPUS
- **Principal Investigator:** RICHARD SAITZ
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $451,709
- **Award type:** 1
- **Project period:** 2021-09-22 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10304667

## Citation

> US National Institutes of Health, RePORTER application 10304667, Administrative Core (1P01AA029546-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10304667. Licensed CC0.

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