# Examining Biobehavioral Mechanisms of Extreme Eating Behaviors in Young Children with ASD

> **NIH NIH F32** · UNIVERSITY OF KANSAS LAWRENCE · 2022 · $53,401

## Abstract

PROJECT SUMMARY
Children with ASD have a fivefold increase in eating problems when compared to typically developing children.
These extreme eating behaviors often lead to serious health consequences (e.g., malnutrition, obesity) and are
cause for significant parental stress and burden. We have yet to truly understand the mechanisms associated
with these difficult behaviors in children with ASD, and there is no standard of care to treat feeding issues in
ASD, perhaps because our current feeding interventions are not mechanistically-informed. Thus, this study
uses a biobehavioral approach to uncover these mechanisms by drawing from other eating disordered
populations that show symptom overlap with ASD. Neurobehavioral models of eating behavior link the role of
attention in maintaining extreme eating behaviors, and this study will use innovative eye-tracking technology to
objectively examine attentional bias towards food. Further, we will examine how behaviorally expressed
symptoms of ASD (e.g., repetitive behaviors) are associated with these food-related attentional mechanisms.
Lastly, given the environment is likely to influence children’s eating behaviors, we will examine how the home
environment affects the eating behaviors of children with ASD. Our aims include: Aim 1: To use eye-tracking
technology to examine food-related attentional biases in children with ASD compared to TD children. Aim 2:
To examine if we can reliably measure the naturalistic characteristics of the environment and eating behaviors
of children with ASD at home. Exploratory Aim 3: To explore if behaviorally expressed symptoms of ASD are
associated with food attentional biases. Training goals for this study will involve: 1) advanced training in
eye tracking, 2) obtaining a strong basis in research design, methodology, and observational data collection, 3)
strengthening statistical knowledge, 4) expanding clinical knowledge of eating behaviors, and 5) developing
concrete professional development plans leading to independent research funding. The overall impact of this
study will be determining the interplay and driving mechanisms of eating behaviors in ASD. We anticipate this
study will provide robust pilot data that will lead to future funding and a larger sample size to determine
underlying mechanisms of eating behaviors in children with ASD. Further, given the lack of empirically
validated treatment approaches, and the high rates of treatment resistance for feeding problems in ASD, this
study will provide a basis towards biologically informed eating interventions for children with ASD to reduce
deleterious health consequences associated with extreme eating behaviors.

## Key facts

- **NIH application ID:** 10307515
- **Project number:** 5F32HD101311-03
- **Recipient organization:** UNIVERSITY OF KANSAS LAWRENCE
- **Principal Investigator:** Anna Wallisch
- **Activity code:** F32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $53,401
- **Award type:** 5
- **Project period:** 2019-12-01 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10307515

## Citation

> US National Institutes of Health, RePORTER application 10307515, Examining Biobehavioral Mechanisms of Extreme Eating Behaviors in Young Children with ASD (5F32HD101311-03). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10307515. Licensed CC0.

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