# Smoking Machine Adaptor Design Project for ENDS, Cigars, and Heated Tobacco Products (UC2)

> **NIH FDA UC2** · OHIO STATE UNIVERSITY · 2022 · $996,891

## Abstract

ABSTRACT
The purpose of the smoking machine adaptor design project is to develop a standardized and validated
adaptor, or family of adaptors, for attachment to existing smoking and vaping machines to ensure the accuracy
and reliability of scientific data obtained from the study of the physical and chemical properties of electronic
nicotine delivery systems (ENDS), cigars, and heated tobacco products (HTPs). Equally important, the project
will produce a set of protocols for the generation and collection of mainstream yield data for these four product
types. For the proposed research efforts, the Ohio State University (prime contractor) will collaborate closely
with the Food and Drug Administration’s Center for Tobacco Products (CTP), and with our proposed team
members, including our Particle and Aerosol Characterization Laboratory, the Centers for Disease Control and
Prevention Tobacco Products Laboratory (CDC-TPL); our smoking and vaping machine industry partner,
Cerulean; and former Borgwaldt KC USA linear smoking machine design implementation engineer, Jeremy
Jones, President, Produced Better. The project is comprised of four main phases: 1) Feasibility, 2) Prototype
Design and Testing, 3) Adaptor Validation, and 4) Continued Stakeholder Support. Once the validation of the
adaptors is complete, our team will be responsible for the manufacture, sale, and continued device support,
including continuous design improvement, of the USMA in the final phase of the project and after CTP
sponsorship has concluded. The project will provide a public benefit by ensuring that stakeholders can
generate accurate scientific data and reduce measurement variability to help fill current scientific gaps
regarding the chemical and physical properties of ENDS, cigars, and HTPs. These data will assist FDA in their
mission to protect Americans from tobacco-related death and disease by regulating tobacco products and by
educating the public, especially young people, about tobacco products and the dangers their use poses to
themselves and others.

## Key facts

- **NIH application ID:** 10308123
- **Project number:** 5UC2FD007229-02
- **Recipient organization:** OHIO STATE UNIVERSITY
- **Principal Investigator:** Marielle Cavanaugh Brinkman
- **Activity code:** UC2 (R01, R21, SBIR, etc.)
- **Funding institute:** FDA
- **Fiscal year:** 2022
- **Award amount:** $996,891
- **Award type:** 5
- **Project period:** 2020-12-01 → 2025-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10308123

## Citation

> US National Institutes of Health, RePORTER application 10308123, Smoking Machine Adaptor Design Project for ENDS, Cigars, and Heated Tobacco Products (UC2) (5UC2FD007229-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10308123. Licensed CC0.

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