# The WashU TaRGET Environmental Epigenomics Data Coordination Center

> **NIH NIH U24** · WASHINGTON UNIVERSITY · 2021 · $750,000

## Abstract

PROJECT SUMMARY
 The goals of the The WashU TaRGET Environmental Epigenomics Data Coordination Center (TaRGET
T2C DCC) component to the TaRGET Consortium are to collect, store, curate, and display all data, metadata,
and analysis tools generated by the TaRGET. The DCC will also assist in the development and dissemination of
metadata and standards to be adopted by the community at large, approaches for integrative analysis of a wide-
range of data types, and visualization and analysis tools to facilitate access and understanding of complex
datasets to non-expert users. Ultimately, the TaRGET Consortium will produce tools, analysis, models, and data
that form the reference maps of the environmental exposure related epigenomes of different cells and tissues,
and we will develop the DCC into a substantial service organization allowing scientific research to take full
advantage of the TaRGET reference maps. To support the TaRGET Consortium, we will establish databases
with an application framework to facilitate complex data loading including detailed experimental descriptions and
metadata; we will define and establish pipelines that connect all Consortium members to the data, and create
avenues of access that distribute the data to the greater biological research community; we will establish
metadata requirements, controlled vocabularies, standardized data formats, and quality control metrics for all
TaRGET data; we will bring together laboratories that generate complex data types via experimental assays with
laboratories that integrate these data using computational tools to define the epigenomic programs in the context
of environmental exposure. Through the creation of structures data flow pipelines for the verification and
validation of all data, and providing processes for the documentation of metadata, the DCC will enhance the
TaRGET data production. The DCC will also coordinate integrative data analysis by creating and adapting
analysis pipelines, and by developing advanced Genome Browser functions for the visual integration of TaRGET
data. In addition, we will create TaRGET Data Portal that will be the primary entry point to the wealth of
experimental data as well as computational analyses. The Portal will integrate these data resources and make
them available via enhanced search and browsing capabilities. Finally, the DCC will provide documentation,
training, and outreach via many media including written documentation, video tutorials, online books, webinars,
and meeting workshops and presentations.

## Key facts

- **NIH application ID:** 10310801
- **Project number:** 3U24ES026699-05S1
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** Ting Wang
- **Activity code:** U24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $750,000
- **Award type:** 3
- **Project period:** 2016-07-01 → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10310801

## Citation

> US National Institutes of Health, RePORTER application 10310801, The WashU TaRGET Environmental Epigenomics Data Coordination Center (3U24ES026699-05S1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10310801. Licensed CC0.

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