# California National Primate Research Center

> **NIH NIH P51** · UNIVERSITY OF CALIFORNIA AT DAVIS · 2021 · $40,119

## Abstract

PROJECT ABSTRACT
This application from the California National Primate Research Center (CNPRC) located on the University of California
(UC) Davis campus, seeks to obtain federal funding in the amount of $3,100,000 through the Administrative
Supplements for Alteration and Renovation (A&R) and expansion of breeding to provide rhesus macaques for COVID-
19 research. The Alteration and Renovation funds will be used to renovate a shade structure for a single ½ acre outdoor
corral, perform repairs to the interior corral structure, and renovate and provide heating to five outdoor pens. The
breeding colony expansion for the CNPRC breeding colony will begin in Year 1 and continue in Year 2. Two previously
renovated outdoor breeding corrals will be populated with approximately seventy rhesus macaques in each corral in
Year 1. The five outdoor pens that are renovated and have heating installed will be used for animal production in Year
2. These outdoor pens are smaller and house approximately 10-15 animals. The CNPRC will acquire forty young rhesus
macaques from the Caribbean Primate Research Center (CPRC) in Year 1. These animals will complete the CNPRC
90 day quarantine and will then be housed in the smaller outdoor pens for repeated testing to confirm their viral status
before combining them with juvenile rhesus from the CNPRC colony. We will also use ten indoor gang cages for housing
of young rhesus, formation of stable social groups, repeat viral screening, and eventual transfer to breeding corrals in
the future. The corral that is renovated in Year 1 will then be used to house an additional 70 animals to form the third
breeding corral for colony expansion. The forty young rhesus acquired from the CPRC will be integrated into the third
breeding corral along with smaller breeding groups in the outdoor pens. Funds are requested in Year 2 to pay the per
diem for the expanded breeding group as well as hire additional staff to provide for the animal care, colony management,
and veterinary care needs. This funding for additional staff is needed because by Year 2 we will designate approximately
350 animals including the forty animals from the CPRC for breeding and overall colony expansion. Their primary
assignment will be to the expanded breeding colony. When the 200 females begin breeding, the estimated production
(77% live birth rate/female) will produce an additional 154 rhesus on an annual basis for COVID and pandemic focused
research.
The specific aims of the proposed project are to:
 • Renovate one ½ acre corral and five outdoor pens to be used for expansion of the CNPRC breeding colony
 • Establish three additional breeding corrals, five outdoor pens, and ten indoor gang cages for expanded
 breeding for COVID-19 and future pandemic research
 • Expand CNPRC animal care, colony management, behavior and veterinary staff to provide care
 for the expanded colony
 • Commit 350 adult rhesus to an expanded breeding colony with the goal of increasing current
 C...

## Key facts

- **NIH application ID:** 10313859
- **Project number:** 3P51OD011107-59S8
- **Recipient organization:** UNIVERSITY OF CALIFORNIA AT DAVIS
- **Principal Investigator:** Prasant Mohapatra
- **Activity code:** P51 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $40,119
- **Award type:** 3
- **Project period:** 2021-02-12 → 2023-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10313859

## Citation

> US National Institutes of Health, RePORTER application 10313859, California National Primate Research Center (3P51OD011107-59S8). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10313859. Licensed CC0.

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