# Race/ethnic Differences Among Older Patients with Type 2 Diabetes at Risk for Hypoglycemia

> **NIH NIH R01** · KAISER FOUNDATION RESEARCH INSTITUTE · 2021 · $88,689

## Abstract

Project Summary
 Many older adults with type 2 diabetes (T2D) experience dangerous hypoglycemic due to intensive T2D
 medication treatment. The decision to reduce treatment intensity must be informed by patient preferences and
 values. New tools that educate patients and build their communication skills to voice their preferences offer a
 promising strategy for improving the safety of T2D care in high risk older adults.The goal of this R01 award is
 to apply principles of values elicitation and skill building for communication and decision making to the specific
 clinical problem of hypoglycemia-related adverse outcomes in vulnerable older patients. The aims of the
 parent R01 are to develop an online tool to specifically address T2D treatment intensity in older adults at
 increased risk for hypoglycemic events, and to then conduct a randomized trial to assess the efficacy of this
 new tool to reduce hypoglycemia events among high risk patients ≥ 75 years of age. Our approach to support
 value-aligned care represents an innovative and potentially widely applicable method to help older adults to
 make informed decisions based on their goals and preferences. If successful, this framework could be scaled
 and applied in a wide variety of healthcare settings and chronic conditions in which evolving risks, benefits,
 and consequences of treatment require re-assessment with age. The addition of Dana Abdelgadir through
 this Administrative Supplement will provide the project with the excellent opportunity to conduct more detailed
 analyses of African American participants in our clinical trial (approximately 12% of expected participants,
 similar proportion to the source population in Northern California) by allowing an increased emphasis on
 examining the similarities and unique differences in how older African American patients with diabetes engage
 with the health care system and to current medication-related practices. Further study focused on older
 African Americans in our trial has the potential to provide useful insight into how to best engage this patient
 population in research designed to improve engagement and reduce medication risk. The proposed research
 is directly related to the main goals of the parent grant while also broadening our project by extending our
 comparative analyses of African American patients. This study addresses the three NIH priorities of
 translating evidence into practice, improving medication safety, and understanding health care disparities. The
 specific project proposed within the Under-Represented Minority (URM) Administrative Supplement will focus
 on a more detailed examination of older African American patients with type 2 diabetes at increased risk for
 hypoglycemia. This supplemental work will provide further insight into the potential disparities and unique
 barriers to communication faced by older African Americans during primary care visits.

## Key facts

- **NIH application ID:** 10318875
- **Project number:** 3R01AG068133-02S1
- **Recipient organization:** KAISER FOUNDATION RESEARCH INSTITUTE
- **Principal Investigator:** RICHARD W GRANT
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $88,689
- **Award type:** 3
- **Project period:** 2020-08-15 → 2025-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10318875

## Citation

> US National Institutes of Health, RePORTER application 10318875, Race/ethnic Differences Among Older Patients with Type 2 Diabetes at Risk for Hypoglycemia (3R01AG068133-02S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10318875. Licensed CC0.

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