# Antitumor Assessment

> **NIH NIH P30** · SLOAN-KETTERING INST CAN RESEARCH · 2022 · $230,112

## Abstract

ABSTRACT
The Antitumor Assessment Core provides support for early discovery of effective antitumor agents and
therapeutics. The Core provides resources, professional and technical expertise and advisory services related
to the evaluation of agents with potential therapeutic activity, and works closely with investigators to establish
in vivo mouse models, including Patient Derived Xenograft (PDX) models, for the design and execution of
pharmacokinetic, toxicity and in vivo efficacy studies. The Core also determines the best formulation,
administration route, and treatment schedule for each new compound, either alone or in combination with other
agents. As such, the Core provides a major vehicle to facilitate pre-clinical studies, including GLP-compliant
safety toxicology studies in support of IND applications, and is a major contributor to the translational mission
of the Center. The Core helps investigators to design, plan, and execute their in vivo experiments, prepare
animal protocols and grant applications involving animal studies, and analyze and summarize data for
publication and for IND reporting. Importantly, the Core acts as a central coordinator for studies involving
support from several Core facilities (including Animal Imaging, Comparative Medicine and Pathology, Tissue
Procurement Service, Organic Synthesis, Integrated Genomics, Radiochemistry and Molecular Imaging
Probes, and Molecular Cytology) so that studies are carried out properly and in a time- and cost-efficient
manner.

## Key facts

- **NIH application ID:** 10319503
- **Project number:** 5P30CA008748-56
- **Recipient organization:** SLOAN-KETTERING INST CAN RESEARCH
- **Principal Investigator:** Elisa de Stanchina
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $230,112
- **Award type:** 5
- **Project period:** 1997-01-20 → 2023-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10319503

## Citation

> US National Institutes of Health, RePORTER application 10319503, Antitumor Assessment (5P30CA008748-56). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10319503. Licensed CC0.

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