# JAK-STAT Control of Zika Virus-Induced Fetal Injury

> **NIH NIH R01** · UNIVERSITY OF WASHINGTON · 2021 · $328,382

## Abstract

Project Summary
The current project, "Jak STAT control of Zika virus-induced fetal injury" (R01 AI143265), includes
the processing of many nonhuman primate (NHP) and human tissue and cell samples for high
throughput RNA sequencing (RNAseq) analysis. Our sample-processing pipeline for these
assays includes RNA isolation and quality control (QC), and library construction and library QC.
We currently utilize a Biomek FX automated workstation to perform the majority of these work
steps in handling high volume samples in our high throughput workload for these analyses. The
Biomek FX is 10 years old. Due to the age, it is not reliable, the ability to obtain a future service
contract is not guaranteed, and the current configuration and software are not compatible with off-
the-shelf protocols. Thus, we are in need of funds to replace this instrument. The purchase of a
Biomek i7 Hybrid automated workstation to replace our Biomek FX workstation, allows us to
achieve our stated project goals.
0

## Key facts

- **NIH application ID:** 10321508
- **Project number:** 3R01AI143265-02S1
- **Recipient organization:** UNIVERSITY OF WASHINGTON
- **Principal Investigator:** Kristina M. Adams Waldorf
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $328,382
- **Award type:** 3
- **Project period:** 2021-02-10 → 2021-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10321508

## Citation

> US National Institutes of Health, RePORTER application 10321508, JAK-STAT Control of Zika Virus-Induced Fetal Injury (3R01AI143265-02S1). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10321508. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*