# Improved Delivery System for Drug-Coated Balloon Therapy

> **NIH NIH R43** · MINNESOTA HEALTHSOLUTIONS CORPORATION · 2021 · $299,299

## Abstract

Project Summary/Abstract
We propose to develop a novel angioplasty balloon inflation system to improve the efficacy of drug-coated
balloon angioplasty. Atherosclerosis, characterized by the deposition of plaques of fatty material on the inner
walls of arteries, can lead to the development of peripheral arterial disease (PAD) due to obstructive narrowing
of arteries that supply blood to the extremities. PAD frequently causes a wide variety of ischemic symptoms
including pain, non-healing arterial insufficiency ulcers, lower limb tissue loss and gangrene. Percutaneous
drug-coated balloon angioplasty of PAD blockages has been observed to reduce symptoms, salvage affected
limbs and prolong survival.

## Key facts

- **NIH application ID:** 10324442
- **Project number:** 1R43HL160298-01
- **Recipient organization:** MINNESOTA HEALTHSOLUTIONS CORPORATION
- **Principal Investigator:** Nick Rydberg
- **Activity code:** R43 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $299,299
- **Award type:** 1
- **Project period:** 2021-08-01 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10324442

## Citation

> US National Institutes of Health, RePORTER application 10324442, Improved Delivery System for Drug-Coated Balloon Therapy (1R43HL160298-01). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10324442. Licensed CC0.

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