# Microbiome-Balancing Wraps for Managing Eczema

> **NIH NIH R43** · CFD RESEARCH CORPORATION · 2021 · $253,024

## Abstract

Project Summary/Abstract:
The long-term goal of this project is to develop microbiome-balancing antimicrobial wraps to use in
the treatment of atopic dermatitis or eczema infections. The topical steroids used in the treatment of
atopic dermatitis cause many side-effects and addiction. Additionally, the antibiotics used to treat AD
infections eliminate skin commensals along with the targeted pathogens, resulting in skin microbial
imbalance. Skin commensals play an important role in preventing the re-colonization and re-
occurrence of the eczema by inhibiting the pathogens. Protective wraps or wet wraps made of skin
commensal gentle antimicrobial compounds can prevent atopic dermatitis by promoting the growth of
skin beneficial microbes and inhibiting the skin pathogens. CFD Research has discovered novel
natural product-based compounds with skin commensal gentle targeted antimicrobial activity. In this
proposal we seek to develop skin microbiome-gentle antimicrobial cotton fabrics that can release the
compound at a certain rate to inhibit the pathogens while promoting growth of skin commensals.

## Key facts

- **NIH application ID:** 10324997
- **Project number:** 1R43AT011486-01A1
- **Recipient organization:** CFD RESEARCH CORPORATION
- **Principal Investigator:** Hanumantharao Paritala
- **Activity code:** R43 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $253,024
- **Award type:** 1
- **Project period:** 2021-08-01 → 2023-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10324997

## Citation

> US National Institutes of Health, RePORTER application 10324997, Microbiome-Balancing Wraps for Managing Eczema (1R43AT011486-01A1). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10324997. Licensed CC0.

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