# BU Clinical HIV/AIDS Research Training Program (BU-CHART

> **NIH NIH T32** · BOSTON MEDICAL CENTER · 2021 · $386,763

## Abstract

PROJECT SUMMARY/ABSTRACT
The Boston University Clinical HIV/AIDS Research Training (BU-CHART) program prepares outstanding M.D
and Ph.D. trainees for careers as scientific leaders in HIV/AIDS research, with a focus on research in
disadvantaged and underserved populations. BU-CHART focuses its training plan on four high-priority HIV
research fields that address the substantial challenges that remain to ending the HIV epidemic: 1) substance
use and HIV - a syndemic of substance use disorders and HIV infection fuels HIV outbreaks in the U.S.,
Eastern Europe, and Asia. 2) Tuberculosis and HCV co-infection - comorbidities, including Tuberculosis and
Hepatitis C Virus are leading causes of death among HIV-infected people; 3) HIV transmission and
establishment of latency - HIV incidence remains stubbornly elevated, and early establishment of HIV latency
remains a frustrating puzzle that limits progress to finding HIV cure; 4) HIV treatment and the accelerated
aging process - we still seek safe and effective interventions to reduce the inappropriate immune activation that
accompanies HIV infection and leads to end-organ disease. The training facilities include state-of-the-art
research space at Boston University Schools of Medicine and Public Health and Boston Medical Center, the
largest Safety-net hospital in New England. BU-CHART synergizes with existing training programs on campus,
including the BU Clinical and Translational Science Institute (CTSI), the Providence-Boston Center for AIDS
Research, and other T32- and R25-funded training programs on the BUMC campus. We pair our outstanding
trainees with BU-CHART faculty mentors who are established investigators with NIH-funded research projects
and experience mentoring. We provide a thoughtfully constructed training plan in scientific reasoning and
experimental design, professional development, and the ethical conduct of human research. The result is a
track record of training success. In the past 15 years, BU-CHART trained 26 MD and PhD post-doctoral
fellows, of whom 20 (77%) remain in in academic positions focused on HIV research. Among the 7 trainees
who completed the program in the current grant cycle, 6 now have academic research positions, 3 have
already obtained career development awards, and 2 have career development awards currently under review.

## Key facts

- **NIH application ID:** 10326682
- **Project number:** 2T32AI052074-16A1
- **Recipient organization:** BOSTON MEDICAL CENTER
- **Principal Investigator:** Benjamin P. Linas
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $386,763
- **Award type:** 2
- **Project period:** 2003-08-01 → 2026-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10326682

## Citation

> US National Institutes of Health, RePORTER application 10326682, BU Clinical HIV/AIDS Research Training Program (BU-CHART (2T32AI052074-16A1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10326682. Licensed CC0.

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