# Pilot Project: Racial Disparities in Lung Cancer Screening Among a High-Risk  Population at a Community Hospital and an Academic Health System in the Southeastern US

> **NIH NIH U54** · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2021 · $88,640

## Abstract

PILOT PROJECT: SUMMARY ABSTRACT
Each year, 206,000 people in the US are diagnosed with lung cancer, and 160,000 die of this disease. Lung
cancer incidence and mortality rates, which vary by sex and race, are currently decreasing slowly, but the rates
are higher among African American (AA) males compared to their White counterparts. In Alabama and Georgia,
high lung cancer incidence and mortality rates are attributed to high smoking rates among underserved and low-
income populations. In the US, only 15% of lung cancers are diagnosed at the localized stage, resulting in a poor
overall five-year survival of 17%, but early detection could avert approximately 12,000 lung cancer deaths per
year. The National Lung Screening Trial (NLST) documented a 20% reduction in lung cancer mortality among
those screened. Thus, in 2013, the US Preventive Services Task Force (USPSTF) began recommending annual
screenings for lung cancer with low-dose CT scans (LDCT) for adults aged 55–80 years who have a history of
30-pack-year smoking and either currently smoke or have quit within the past 15 years. Yet, only 3.9% of eligible
individuals underwent screening in 2015. When lung cancer is detected at a local stage (Stage I or II), the 5-year
relative survival rate for AAs is 47%; however, only 15% of lung cancer cases in AAs are detected early, and
lung cancer screening (LCS) for AAs is half of that for White populations. Consistent with the national number,
4.2% of those eligible in Alabama and 4.4% of those eligible in Georgia have been screened for lung cancer,
with no known literature on the sociodemographic breakdown. Although LCS uptake is low among all eligible
individuals, individuals of lower income and those who face barriers to care are likely to be the left behind in the
implementation of LCS programs. We propose to collect LCS data at Grady Memorial Hospital (Atlanta) and at
the University of Alabama at Birmingham (UAB). For these institutions, there is no current information regarding
uptake patterns of LCS. For many patients, the point of first contact with the healthcare system are providers
who can be involved in recommending LCS tests to and/or interpreting their results for patients. The availability
of proven strategies that can reduce lung cancer deaths warrants immediate study of the determinants that limit
maximal use of LCS across areas of greatest need, in particular, high-risk regions in the Southeastern US. Thus,
the objectives of this joint project between Morehouse School of Medicine and UAB are to characterize patients
who were screened and not screened for lung cancer; examine patterns of uptake to LCS in two different health
care systems; and explore barriers and facilitators to LCS at the system, provider, and patient levels for the
development of a multi-level intervention. In accordance with the overall mission of the U54 Partnership between
MSM, TU, and the UAB OCCC, this research will enhance our understanding of cancer disparities ...

## Key facts

- **NIH application ID:** 10328131
- **Project number:** 2U54CA118948-16
- **Recipient organization:** UNIVERSITY OF ALABAMA AT BIRMINGHAM
- **Principal Investigator:** Soumya J Niranjan
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $88,640
- **Award type:** 2
- **Project period:** 2005-09-23 → 2024-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10328131

## Citation

> US National Institutes of Health, RePORTER application 10328131, Pilot Project: Racial Disparities in Lung Cancer Screening Among a High-Risk  Population at a Community Hospital and an Academic Health System in the Southeastern US (2U54CA118948-16). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10328131. Licensed CC0.

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