# Biostatistics and Bioinformatics Core

> **NIH NIH P30** · UNIVERSITY OF PENNSYLVANIA · 2022 · $2,137

## Abstract

PROJECT SUMMARY – Biostatistics and Bioinformatics Core 
The NCI Cancer Center Support Grant (CCSG) to the Abramson Cancer Center (ACC) has funded the 
Biostatistics and Bioinformatics Core (BBC), formerly the Biostatistics Core, continuously since its 
establishment in 1978. The BBC was rated “Exceptional” in the 2015 renewal as part of a Shared Resources 
Group (per the old FOA). In the current funding period, the BBC added expertise in methods for analysis of big 
health data such as `omics data and electronic health records data. ACC-supported bioinformatics services 
were consolidated to enhance centralized availability and cost-efficiency in the BBC. The BBC provides expert 
biostatistical, bioinformatics, and data management guidance in the design, conduct and analysis of research 
projects conducted by ACC members, and offers training in all aspects of design and analysis. Core personnel 
apply existing design and analysis methodologies, and also adapt or develop new methods to address novel 
design and analysis issues arising in cancer studies. A major BBC responsibility is to support the design and 
conduct of clinical trials. As such, the BBC plays a key role in the Protocol Review and Monitoring System, 
particularly through the Clinical Trials Scientific Review and Monitoring Committee. Qi Long, PhD, Professor of 
Biostatistics, has served as BBC Director since 2016 and leads an accomplished and highly collaborative team 
primarily drawn from the faculty of the Department of Biostatistics, Epidemiology and Informatics in the 
Perelman School of Medicine. In the current funding period, the BBC continued to be a dynamic presence in 
the ACC, providing collaborative biostatistical, bioinformatics and data management support to ACC members 
in basic, translational, clinical, and population science research as well as in community outreach and 
engagement activities. BBC members co-authored more than 300 cancer-related publications; collaboration 
with the BBC was essential to the funding of many cancer-related grants, including seven P01s, three P50s, 
one P42, three U54s, and two U24s in areas such as skin, pancreatic, lung, breast, thoracic, cervical, and 
esophageal cancers, hematologic malignancies, smoking cessation research, and environmental 
carcinogenesis, as well as 27 R01s, one R37 and numerous R21s, K-series grants, and foundation and state 
government grants. In addition, BBC members provided key support to monitor cancer incidence and mortality 
in the catchment area. ACC members accounted for 93 of 93 investigators (100%) using the Shared Resource 
during the most recent reporting period (07/01/18 – 06/30/19). In summary, the BBC is composed of a superbly 
qualified, productive, versatile and highly collaborative team of biostatistics, bioinformatics and data 
management professionals who are deeply involved in supporting research and community outreach and 
engagement activities in the ACC. The services provided by the BB...

## Key facts

- **NIH application ID:** 10330979
- **Project number:** 5P30CA016520-46
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** Robert H. Vonderheide
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2022
- **Award amount:** $2,137
- **Award type:** 5
- **Project period:** 1997-01-15 → 2025-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10330979

## Citation

> US National Institutes of Health, RePORTER application 10330979, Biostatistics and Bioinformatics Core (5P30CA016520-46). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10330979. Licensed CC0.

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